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Table 3 Adjusted mean differences and 95% confidence intervals in CSF protein concentrations of the five synaptic measures between biomarker groups.

From: CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

Group comparisonNg22 (pg/ml)Ng36 (pg/ml)SNAP-25tot (pM)SNAP-25aa40 (pM)Synaptotagmin-1 (pM)
FTD vs AD biomarker group− 117.7 (− 193.8, − 54.2)− 54.0 (− 124.0, 10.3)− 21.9 (− 35.6, − 8.0)− 5.7 (− 8.7, − 2.6)− 88.6 (− 168.0, − 18.9)
FTD biomarker vs control group− 22.7 (− 78.4, 33.6)41.7 (− 1.7, 84.0)− 3.9 (− 11.4, 4.2)0.5 (− 1.1, 2.3)− 37.4 (− 80.4, 2.9)
AD biomarker vs control group95.0 (10.5, 169.6)95.7 (20.7, 173.3)18.0 (2.5, 32.4)6.2 (2.9, 9.4)51.2 (− 30.3, 130.5)
  1. Significant differences are shown in italics