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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: ABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOEε4-associated Alzheimer’s disease

Fig. 1

An APOE-ABCA7 (rs3764650) interaction effect on functional connectivity in the default mode network anchored by the right entorhinal seed (a) and left posterior cingulate cortical seed (b), and the correlation between the genetic interaction-associated neural activity and memory scores in the CVVLT-10 min and CVVLT-cued tests. Residuals are plotted to determine the correlation between each variable. The 95% confidence interval is the area enclosed by the dashed curves. (x, y, z), coordinates on Montreal Neurological Institute template brain; CVVLT, Chinese version of the Verbal Learning Test; G-allele-carriers, ABCA7 rs3764650G allele carriers; TT-carriers, ABCA7 rs3764650T homozygous carriers

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