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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Rescue of cognitive deficits in APP/PS1 mice by accelerating the aggregation of β-amyloid peptide

Fig. 3

| ZGM1 has low cytotoxicity and can effectively reduce the cytotoxicity of Aβ. a, b CCK8 assays. SH-SY5Y cells and neurons were treated with different concentrations of ZGM1 for 48 h. Cell viability was normalized to that of the DMSO-treated cells. a SH-SY5Y cells. b Neurons. c, d CCK8 assays. SH-SY5Y cells and neurons were treated with ZGM1 (5 μM), Aβ (5 μM), ZGM1+ Aβ (5 μM + 5 μM), and the same content of DMSO as the other samples for 2 days. c SH-SY5Y cells. d Neurons. The error bars represent the S.D. One-way analysis of variance was performed (*P < 0.05, **P < 0.01, ***P < 0.001; n/s were not significant)

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