Characteristics | HR (95% CI) | |
---|---|---|
Any dementia | AD dementia | |
Cognition | ||
RAVLT, immediate recall score | 0.92 (0.88–0.97) | 0.93 (0.88–0.99) |
RAVLT, delayed recall score | 0.79 (0.69–0.91) | 0.84 (0.72–0.99) |
Vascular factors | ||
Systolic BP, mmHg | 1.03 (1.01–1.05) | 1.02 (0.99–1.04) |
Diastolic BP, mmHg | 1.01 (0.98–1.05) | 0.98 (0.94–1.03) |
BMI, kg/m2 | 0.89 (0.80–0.99) | 0.95 (0.82–1.11) |
Current smoking | 1.21 (0.46–3.18) | 1.29 (0.37–4.52) |
Hypertension | 1.28 (0.69–2.39) | 1.34 (0.60–2.97) |
Hyperlipidemia | 0.87 (0.45–1.68) | 0.51 (0.21–1.26) |
Diabetes | 0.68 (0.31–1.46) | 0.89 (0.36–2.20) |
CAIDE risk score | 0.99 (0.82–1.19) | 1.03 (0.79–1.34) |
CAIDE risk score with APOE | 1.29 (0.86–1.93) | 1.49 (0.81–2.75) |
Other factors | ||
MTA score > 1 | 2.21 (1.09–4.45) | 2.60 (1.08–6.29) |
APOE ε4 genotype | 2.07 (0.83–5.17) | 3.28 (1.11–9.71) |
Family history of dementia | 0.62 (0.30–1.29) | 0.57 (0.22–1.47) |
Cornell score | 0.94 (0.87–1.02) | 0.85 (0.75–0.97) |