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Table 4 Agreement of INNOTEST and Lumipulse biomarker and ratio results on the training cohort

From: Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer’s disease

INNOTEST

Lumipulse

OPA

Negative

Positive

 

Aβ42

 Negative

41 (34.2%)

4 (3.3%)

114 (95.0%)

 Positive

2 (1.7%)

73 (60.8%)

t-Tau

 Negative

40 (33.3%)

0 (0.0%)

116 (96.7%)

 Positive

4 (3.3%)

76 (63.3%)

p-Tau

 Negative

34 (28.3%)

7 (5.8%)

105 (87.5%)

 Positive

8 (6.7%)

71 (59.2%)

Aβ42/Aβ40

 Negative

33 (27.5%)

10 (8.3%)

105 (87.5%)

 Positive

5 (4.2%)

72 (60.0%)

Aβ42/t-Tau

 Negative

39 (32.5%)

1 (0.8%)

117 (97.5%)

 Positive

2 (1.7%)

78 (65.0%)

Aβ42/p-Tau

 Negative

38 (31.7%)

5 (4.2%)

113 (94.2%)

 Positive

2 (1.7%)

75 (62.5%)

CSF-AD profile

 Negative

34 (28.3%)

8 (6.7%)

108 (90.0%)

 Positive

4 (3.3%)

74 (61.7%)

  1. Data are expressed as the number of patients (percentage in relation to total). OPA overall percentage of agreement