Fig. 4

Heat maps showing predicted probability of being Aβ-PET(+) based on TP42/40 and age stratified for APOE genotype. Predicted probabilities in APOE Ɛ4 non-carriers (a) and APOE Ɛ4 carriers (b). Probabilities are displayed as percentages. Note that TP42/40 decreases upward in axis for optimal visualization purposes. It should be noted that probabilities were predicted from a logistic regression model modeling expected probabilities in the age range most likely present during pre-screening or clinical assessment. These predicted probabilities could be more accurately determined in a larger population including the complete age range