Fig. 3From: Association between insomnia and cognitive performance, gray matter volume, and white matter microstructure in cognitively unimpaired adultsInteractions between APOE-ε4 status and insomnia in gray matter volume. a Gray matter areas where a significant interaction between APOE-ε4 status and insomnia was found (puncorrected < 0.005; k = 100, only the additive model is shown). Graphs b–e show how the association between APOE status and gray matter volume is modulated by the presence of insomnia in four representative brain regions. L, left hemisphere; R, right hemisphereBack to article page