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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer’s disease: a longitudinal multimodal in vivo study

Fig. 2

Retinal function in WT and 3×Tg-AD mice at 4, 8, 12, and 16 months of age assessed by fERG, under scotopic conditions. Main component values obtained in response to 0.0095 cd.s/m2 light stimulus (brod) or 9.49 cd.s/m2 light stimulus (amix, bmix, and OP1) in WT (white bars) and 3×Tg-AD (black bars): a amix amplitude, b brod amplitude, c bmix amplitude, d OP1 amplitude. The results are presented as mean ± SEM. *p < 0.05, **p < 0.01, and ***p < 0.001 according to Student’s t test. nWT: at 4 months = 19, at 8 months = 19, at 12 months = 17, at 16 months = 17; n3×Tg-AD: at 4 months = 23, at 8 months = 23, at 12 months = 22, at 16 months = 22

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