Skip to main content

Advertisement

Table 3 Multiple logistic regression analysis with midlife and current sleep qualities as independent variables and Aβ positivity as a dependent variable

From: Sleep experiences during different lifetime periods and in vivo Alzheimer pathologies

Covariates aOR (95% CI) p value
Age 1.112 (1.041–1.188) 0.002
Gender 1.043 (0.424–2.563) 0.927
Education 1.056 (0.954–1.168) 0.292
APOE4 status 3.314 (1.297–8.467) 0.012
Vascular risk score 0.987 (0.960–1.015) 0.357
Use of sleep pill 4.606 (0.715–29.659) 0.108
HDRS 0.833 (0.572–1.212) 0.340
Midlife sleep quality 3.796 (1.117–12.895)a 0.033
Current sleep quality 3.183 (0.793–12.779)a 0.103
  1. beta-amyloid, aOR adjusted odds ratio, CI confidence interval, APOE4 apolipoprotein E ε4, HDRS Hamilton Depression Rating Scale
  2. aGood sleep quality was taken as a reference, so aOR represents the likelihood of being Aβ positive for bad sleep quality compared with good one