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Table 3 Multiple logistic regression analysis with midlife and current sleep qualities as independent variables and Aβ positivity as a dependent variable

From: Sleep experiences during different lifetime periods and in vivo Alzheimer pathologies

Covariates

aOR (95% CI)

p value

Age

1.112 (1.041–1.188)

0.002

Gender

1.043 (0.424–2.563)

0.927

Education

1.056 (0.954–1.168)

0.292

APOE4 status

3.314 (1.297–8.467)

0.012

Vascular risk score

0.987 (0.960–1.015)

0.357

Use of sleep pill

4.606 (0.715–29.659)

0.108

HDRS

0.833 (0.572–1.212)

0.340

Midlife sleep quality

3.796 (1.117–12.895)a

0.033

Current sleep quality

3.183 (0.793–12.779)a

0.103

  1. Aβ beta-amyloid, aOR adjusted odds ratio, CI confidence interval, APOE4 apolipoprotein E ε4, HDRS Hamilton Depression Rating Scale
  2. aGood sleep quality was taken as a reference, so aOR represents the likelihood of being Aβ positive for bad sleep quality compared with good one
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Alzheimer's Research & Therapy

ISSN: 1758-9193