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Table 1 Rate of discordance across diagnostic groups

From: Discordant amyloid-β PET and CSF biomarkers and its clinical consequences

 

Total

SCD

MCI

AD dementia

Non-AD dementia

N (%)

768

194 (25)

127 (17)

309 (40)

138 (18)

 Discordant, cut-off < 813 ng/L (%)*

97 (13)

30 (15)

17 (13)

28 (9)

22 (16)

CSF+/PET− (%)

65 (67)

20 (67)

9 (53)

17 (61)

19 (86)

 Discordant, excl. ± 5% cut-off (%)

75 (11)

27 (15)

14 (12)

15 (5)

19 (15)

 Discordant, excl. ± 10% cut-off (%)

56 (9)

20 (12)

10 (10)

13 (5)

13 (11)

  1. Abbreviations: AD Alzheimer’s disease, CSF cerebrospinal fluid, MCI mild cognitive impairment, PET positron emission tomography, SCD subjective cognitive decline
  2. *Proportion of discordant patients between diagnostic groups does not differ significantly (chi-squared test)