TY - JOUR AU - Xu, J. AU - Murphy, S. L. AU - Kochanek, K. D. AU - Bastian, B. AU - Arias, E. PY - 2018 DA - 2018// TI - Deaths: final data for 2016 JO - Natl Vital Stat Rep VL - 67 ID - Xu2018 ER - TY - JOUR PY - 2018 DA - 2018// TI - 2018 Alzheimer’s disease facts and figures JO - Alzheimers Dement VL - 14 UR - https://doi.org/10.1016/j.jalz.2018.02.001 DO - 10.1016/j.jalz.2018.02.001 ID - ref2 ER - TY - JOUR AU - Hogan, D. B. PY - 2014 DA - 2014// TI - Long-term efficacy and toxicity of cholinesterase inhibitors in the treatment of Alzheimer disease JO - Can J Psychiatr VL - 59 UR - https://doi.org/10.1177/070674371405901202 DO - 10.1177/070674371405901202 ID - Hogan2014 ER - TY - JOUR AU - Emre, M. AU - Mecocci, P. AU - Stender, K. PY - 2008 DA - 2008// TI - Pooled analyses on cognitive effects of memantine in patients with moderate to severe Alzheimer’s disease JO - J Alzheimers Dis VL - 14 UR - https://doi.org/10.3233/JAD-2008-14207 DO - 10.3233/JAD-2008-14207 ID - Emre2008 ER - TY - JOUR AU - Areosa, S. A. AU - Sherriff, F. AU - McShane, R. PY - 2005 DA - 2005// TI - Memantine for dementia JO - Cochrane Database Syst Rev. VL - 3 ID - Areosa2005 ER - TY - JOUR AU - Simic, G. AU - Babic Leko, M. AU - Wray, S. AU - Harrington, C. AU - Delalle, I. AU - Jovanov-Milosevic, N. AU - Bazadona, D. AU - Buee, L. AU - Silva, R. AU - Giovanni, G. PY - 2016 DA - 2016// TI - Tau protein hyperphosphorylation and aggregation in Alzheimer’s disease and other tauopathies, and possible neuroprotective strategies JO - Biomolecules VL - 6 UR - https://doi.org/10.3390/biom6010006 DO - 10.3390/biom6010006 ID - Simic2016 ER - TY - JOUR AU - Barage, S. H. AU - Sonawane, K. D. PY - 2015 DA - 2015// TI - Amyloid cascade hypothesis: pathogenesis and therapeutic strategies in Alzheimer’s disease JO - Neuropeptides VL - 52 UR - https://doi.org/10.1016/j.npep.2015.06.008 DO - 10.1016/j.npep.2015.06.008 ID - Barage2015 ER - TY - JOUR AU - Rudy, C. C. AU - Hunsberger, H. C. AU - Weitzner, D. S. AU - Reed, M. N. PY - 2015 DA - 2015// TI - The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer’s disease JO - Aging Dis VL - 6 UR - https://doi.org/10.14336/AD.2014.0423 DO - 10.14336/AD.2014.0423 ID - Rudy2015 ER - TY - JOUR AU - Gold, M. PY - 2017 DA - 2017// TI - Phase II clinical trials of anti-amyloid beta antibodies: when is enough, enough? JO - Alzheimers Dement (N Y) VL - 3 ID - Gold2017 ER - TY - JOUR AU - Behl, C. PY - 2017 DA - 2017// TI - Amyloid in Alzheimer’s disease: guilty beyond reasonable doubt? JO - Trends Pharmacol Sci VL - 38 UR - https://doi.org/10.1016/j.tips.2017.07.002 DO - 10.1016/j.tips.2017.07.002 ID - Behl2017 ER - TY - JOUR AU - Mehta, D. AU - Jackson, R. AU - Paul, G. AU - Shi, J. AU - Sabbagh, M. PY - 2017 DA - 2017// TI - Why do trials for Alzheimer’s disease drugs keep failing? A discontinued drug perspective for 2010-2015 JO - Expert Opin Investig Drugs VL - 26 UR - https://doi.org/10.1080/13543784.2017.1323868 DO - 10.1080/13543784.2017.1323868 ID - Mehta2017 ER - TY - JOUR AU - Medina, M. PY - 2018 DA - 2018// TI - An overview on the clinical development of tau-based therapeutics JO - Int J Mol Sci VL - 19 UR - https://doi.org/10.3390/ijms19041160 DO - 10.3390/ijms19041160 ID - Medina2018 ER - TY - JOUR AU - Javidnia, M. AU - Kurd-Misto, B. AU - Moussa, C. PY - 2017 DA - 2017// TI - An update on clinical trials targeting human tauopathies JO - Clin Trials Degener Dis VL - 2 UR - https://doi.org/10.4103/2542-3975.216580 DO - 10.4103/2542-3975.216580 ID - Javidnia2017 ER - TY - JOUR AU - Braak, H. AU - Braak, E. PY - 1998 DA - 1998// TI - Evolution of neuronal changes in the course of Alzheimer’s disease JO - J Neural Transm Suppl VL - 53 UR - https://doi.org/10.1007/978-3-7091-6467-9_11 DO - 10.1007/978-3-7091-6467-9_11 ID - Braak1998 ER - TY - JOUR AU - Francis, P. T. PY - 2003 DA - 2003// TI - Glutamatergic systems in Alzheimer’s disease JO - Int J Geriatr Psychiatry VL - 18 UR - https://doi.org/10.1002/gps.934 DO - 10.1002/gps.934 ID - Francis2003 ER - TY - JOUR AU - Neary, D. AU - Snowden, J. S. AU - Mann, D. M. AU - Bowen, D. M. AU - Sims, N. R. AU - Northen, B. AU - Yates, P. O. AU - Davison, A. N. PY - 1986 DA - 1986// TI - Alzheimer’s disease: a correlative study JO - J Neurol Neurosurg Psychiatry VL - 49 UR - https://doi.org/10.1136/jnnp.49.3.229 DO - 10.1136/jnnp.49.3.229 ID - Neary1986 ER - TY - JOUR AU - DeKosky, S. T. AU - Scheff, S. W. PY - 1990 DA - 1990// TI - Synapse loss in frontal cortex biopsies in Alzheimer’s disease: correlation with cognitive severity JO - Ann Neurol VL - 27 UR - https://doi.org/10.1002/ana.410270502 DO - 10.1002/ana.410270502 ID - DeKosky1990 ER - TY - JOUR AU - Masliah, E. AU - Ellisman, M. AU - Carragher, B. AU - Mallory, M. AU - Young, S. AU - Hansen, L. AU - DeTeresa, R. AU - Terry, R. D. PY - 1992 DA - 1992// TI - Three-dimensional analysis of the relationship between synaptic pathology and neuropil threads in Alzheimer disease JO - J Neuropathol Exp Neurol VL - 51 UR - https://doi.org/10.1097/00005072-199207000-00003 DO - 10.1097/00005072-199207000-00003 ID - Masliah1992 ER - TY - JOUR AU - Masliah, E. AU - Alford, M. AU - DeTeresa, R. AU - Mallory, M. AU - Hansen, L. PY - 1996 DA - 1996// TI - Deficient glutamate transport is associated with neurodegeneration in Alzheimer’s disease JO - Ann Neurol VL - 40 UR - https://doi.org/10.1002/ana.410400512 DO - 10.1002/ana.410400512 ID - Masliah1996 ER - TY - JOUR AU - Kirvell, S. L. AU - Esiri, M. AU - Francis, P. T. PY - 2006 DA - 2006// TI - Down-regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer’s disease JO - J Neurochem VL - 98 UR - https://doi.org/10.1111/j.1471-4159.2006.03935.x DO - 10.1111/j.1471-4159.2006.03935.x ID - Kirvell2006 ER - TY - JOUR AU - Kashani, A. AU - Lepicard, E. AU - Poirel, O. AU - Videau, C. AU - David, J. P. AU - Fallet-Bianco, C. AU - Simon, A. AU - Delacourte, A. AU - Giros, B. AU - Epelbaum, J. PY - 2008 DA - 2008// TI - Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease JO - Neurobiol Aging VL - 29 UR - https://doi.org/10.1016/j.neurobiolaging.2007.04.010 DO - 10.1016/j.neurobiolaging.2007.04.010 ID - Kashani2008 ER - TY - JOUR AU - Sokolow, S. AU - Luu, S. H. AU - Nandy, K. AU - Miller, C. A. AU - Vinters, H. V. AU - Poon, W. W. AU - Gylys, K. H. PY - 2012 DA - 2012// TI - Preferential accumulation of amyloid-beta in presynaptic glutamatergic terminals (VGluT1 and VGluT2) in Alzheimer’s disease cortex JO - Neurobiol Dis VL - 45 UR - https://doi.org/10.1016/j.nbd.2011.08.027 DO - 10.1016/j.nbd.2011.08.027 ID - Sokolow2012 ER - TY - JOUR AU - Filippini, N. AU - MacIntosh, B. J. AU - Hough, M. G. AU - Goodwin, G. M. AU - Frisoni, G. B. AU - Smith, S. M. AU - Matthews, P. M. AU - Beckmann, C. F. AU - Mackay, C. E. PY - 2009 DA - 2009// TI - Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele JO - Proc Natl Acad Sci U S A VL - 106 UR - https://doi.org/10.1073/pnas.0811879106 DO - 10.1073/pnas.0811879106 ID - Filippini2009 ER - TY - JOUR AU - Dennis, N. A. AU - Browndyke, J. N. AU - Stokes, J. AU - Need, A. AU - Burke, J. R. AU - Welsh-Bohmer, K. A. AU - Cabeza, R. PY - 2010 DA - 2010// TI - Temporal lobe functional activity and connectivity in young adult APOE varepsilon4 carriers JO - Alzheimers Dement VL - 6 UR - https://doi.org/10.1016/j.jalz.2009.07.003 DO - 10.1016/j.jalz.2009.07.003 ID - Dennis2010 ER - TY - JOUR AU - Quiroz, Y. T. AU - Budson, A. E. AU - Celone, K. AU - Ruiz, A. AU - Newmark, R. AU - Castrillon, G. AU - Lopera, F. AU - Stern, C. E. PY - 2010 DA - 2010// TI - Hippocampal hyperactivation in presymptomatic familial Alzheimer’s disease JO - Ann Neurol VL - 68 UR - https://doi.org/10.1002/ana.22105 DO - 10.1002/ana.22105 ID - Quiroz2010 ER - TY - JOUR AU - Dickerson, B. C. AU - Salat, D. H. AU - Greve, D. N. AU - Chua, E. F. AU - Rand-Giovannetti, E. AU - Rentz, D. M. AU - Bertram, L. AU - Mullin, K. AU - Tanzi, R. E. AU - Blacker, D. PY - 2005 DA - 2005// TI - Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD JO - Neurology VL - 65 UR - https://doi.org/10.1212/01.wnl.0000171450.97464.49 DO - 10.1212/01.wnl.0000171450.97464.49 ID - Dickerson2005 ER - TY - JOUR AU - Hamalainen, A. AU - Pihlajamaki, M. AU - Tanila, H. AU - Hanninen, T. AU - Niskanen, E. AU - Tervo, S. AU - Karjalainen, P. A. AU - Vanninen, R. L. AU - Soininen, H. PY - 2007 DA - 2007// TI - Increased fMRI responses during encoding in mild cognitive impairment JO - Neurobiol Aging VL - 28 UR - https://doi.org/10.1016/j.neurobiolaging.2006.08.008 DO - 10.1016/j.neurobiolaging.2006.08.008 ID - Hamalainen2007 ER - TY - JOUR AU - Beagle, A. J. AU - Darwish, S. M. AU - Ranasinghe, K. G. AU - La, A. L. AU - Karageorgiou, E. AU - Vossel, K. A. PY - 2017 DA - 2017// TI - Relative incidence of seizures and myoclonus in Alzheimer’s disease, dementia with Lewy bodies, and frontotemporal dementia JO - J Alzheimers Dis VL - 60 UR - https://doi.org/10.3233/JAD-170031 DO - 10.3233/JAD-170031 ID - Beagle2017 ER - TY - JOUR AU - Rothstein, J. D. AU - Martin, L. AU - Levey, A. I. AU - Dykes-Hoberg, M. AU - Jin, L. AU - Wu, D. AU - Nash, N. AU - Kuncl, R. W. PY - 1994 DA - 1994// TI - Localization of neuronal and glial glutamate transporters JO - Neuron VL - 13 UR - https://doi.org/10.1016/0896-6273(94)90038-8 DO - 10.1016/0896-6273(94)90038-8 ID - Rothstein1994 ER - TY - JOUR AU - Rothstein, J. D. AU - Dykes-Hoberg, M. AU - Pardo, C. A. AU - Bristol, L. A. AU - Jin, L. AU - Kuncl, R. W. AU - Kanai, Y. AU - Hediger, M. A. AU - Wang, Y. AU - Schielke, J. P. AU - Welty, D. F. PY - 1996 DA - 1996// TI - Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate JO - Neuron VL - 16 UR - https://doi.org/10.1016/S0896-6273(00)80086-0 DO - 10.1016/S0896-6273(00)80086-0 ID - Rothstein1996 ER - TY - JOUR AU - Herman, M. A. AU - Jahr, C. E. PY - 2007 DA - 2007// TI - Extracellular glutamate concentration in hippocampal slice JO - J Neurosci VL - 27 UR - https://doi.org/10.1523/JNEUROSCI.3009-07.2007 DO - 10.1523/JNEUROSCI.3009-07.2007 ID - Herman2007 ER - TY - JOUR AU - Bechtholt-Gompf, A. J. AU - Walther, H. V. AU - Adams, M. A. AU - Carlezon, W. A. AU - Ongur, D. AU - Cohen, B. M. PY - 2010 DA - 2010// TI - Blockade of astrocytic glutamate uptake in rats induces signs of anhedonia and impaired spatial memory JO - Neuropsychopharmacology VL - 35 UR - https://doi.org/10.1038/npp.2010.74 DO - 10.1038/npp.2010.74 ID - Bechtholt-Gompf2010 ER - TY - JOUR AU - Pita-Almenar, J. D. AU - Zou, S. AU - Colbert, C. M. AU - Eskin, A. PY - 2012 DA - 2012// TI - Relationship between increase in astrocytic GLT-1 glutamate transport and late-LTP JO - Learn Mem VL - 19 UR - https://doi.org/10.1101/lm.023259.111 DO - 10.1101/lm.023259.111 ID - Pita-Almenar2012 ER - TY - JOUR AU - Heo, S. AU - Jung, G. AU - Beuk, T. AU - Hoger, H. AU - Lubec, G. PY - 2012 DA - 2012// TI - Hippocampal glutamate transporter 1 (GLT-1) complex levels are paralleling memory training in the multiple T-maze in C57BL/6J mice JO - Brain Struct Funct VL - 217 UR - https://doi.org/10.1007/s00429-011-0362-5 DO - 10.1007/s00429-011-0362-5 ID - Heo2012 ER - TY - JOUR AU - Jacob, C. P. AU - Koutsilieri, E. AU - Bartl, J. AU - Neuen-Jacob, E. AU - Arzberger, T. AU - Zander, N. AU - Ravid, R. AU - Roggendorf, W. AU - Riederer, P. AU - Grunblatt, E. PY - 2007 DA - 2007// TI - Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer’s disease JO - J Alzheimers Dis VL - 11 UR - https://doi.org/10.3233/JAD-2007-11113 DO - 10.3233/JAD-2007-11113 ID - Jacob2007 ER - TY - JOUR AU - Scott, H. A. AU - Gebhardt, F. M. AU - Mitrovic, A. D. AU - Vandenberg, R. J. AU - Dodd, P. R. PY - 2011 DA - 2011// TI - Glutamate transporter variants reduce glutamate uptake in Alzheimer’s disease JO - Neurobiol Aging VL - 32 UR - https://doi.org/10.1016/j.neurobiolaging.2010.03.008 DO - 10.1016/j.neurobiolaging.2010.03.008 ID - Scott2011 ER - TY - JOUR AU - Mookherjee, P. AU - Green, P. S. AU - Watson, G. S. AU - Marques, M. A. AU - Tanaka, K. AU - Meeker, K. D. AU - Meabon, J. S. AU - Li, N. AU - Zhu, P. AU - Olson, V. G. AU - Cook, D. G. PY - 2011 DA - 2011// TI - GLT-1 loss accelerates cognitive deficit onset in an Alzheimer’s disease animal model JO - J Alzheimers Dis VL - 26 UR - https://doi.org/10.3233/JAD-2011-110503 DO - 10.3233/JAD-2011-110503 ID - Mookherjee2011 ER - TY - JOUR AU - Takahashi, K. AU - Kong, Q. AU - Lin, Y. AU - Stouffer, N. AU - Schulte, D. A. AU - Lai, L. AU - Liu, Q. AU - Chang, L. C. AU - Dominguez, S. AU - Xing, X. PY - 2015 DA - 2015// TI - Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease JO - J Exp Med VL - 212 UR - https://doi.org/10.1084/jem.20140413 DO - 10.1084/jem.20140413 ID - Takahashi2015 ER - TY - JOUR AU - Lozovaya, N. A. AU - Kopanitsa, M. V. AU - Boychuk, Y. A. AU - Krishtal, O. A. PY - 1999 DA - 1999// TI - Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-D-aspartate receptors in the rat hippocampus JO - Neuroscience VL - 91 UR - https://doi.org/10.1016/S0306-4522(98)00638-1 DO - 10.1016/S0306-4522(98)00638-1 ID - Lozovaya1999 ER - TY - JOUR AU - Tian, G. AU - Lai, L. AU - Guo, H. AU - Lin, Y. AU - Butchbach, M. E. AU - Chang, Y. AU - Lin, C. L. PY - 2007 DA - 2007// TI - Translational control of glial glutamate transporter EAAT2 expression JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M609822200 DO - 10.1074/jbc.M609822200 ID - Tian2007 ER - TY - JOUR AU - Colton, C. K. AU - Kong, Q. AU - Lai, L. AU - Zhu, M. X. AU - Seyb, K. I. AU - Cuny, G. D. AU - Xian, J. AU - Glicksman, M. A. AU - Lin, C. L. PY - 2010 DA - 2010// TI - Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity JO - J Biomol Screen VL - 15 UR - https://doi.org/10.1177/1087057110370998 DO - 10.1177/1087057110370998 ID - Colton2010 ER - TY - JOUR AU - Kong, Q. AU - Chang, L. C. AU - Takahashi, K. AU - Liu, Q. AU - Schulte, D. A. AU - Lai, L. AU - Ibabao, B. AU - Lin, Y. AU - Stouffer, N. AU - Das Mukhopadhyay, C. PY - 2014 DA - 2014// TI - Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection JO - J Clin Invest VL - 124 UR - https://doi.org/10.1172/JCI66163 DO - 10.1172/JCI66163 ID - Kong2014 ER - TY - JOUR AU - Foster, J. B. AU - Zhao, F. AU - Wang, X. AU - Xu, Z. AU - Lin, K. AU - Askwith, C. C. AU - Hodgetts, K. J. AU - Lin, C. G. PY - 2018 DA - 2018// TI - Pyridazine-derivatives enhance structural and functional plasticity of tripartite synapse via activation of local translation in astrocytic processes JO - Neuroscience VL - 388 UR - https://doi.org/10.1016/j.neuroscience.2018.07.028 DO - 10.1016/j.neuroscience.2018.07.028 ID - Foster2018 ER - TY - JOUR AU - Ramsden, M. AU - Kotilinek, L. AU - Forster, C. AU - Paulson, J. AU - McGowan, E. AU - SantaCruz, K. AU - Guimaraes, A. AU - Yue, M. AU - Lewis, J. AU - Carlson, G. PY - 2005 DA - 2005// TI - Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L) JO - J Neurosci VL - 25 UR - https://doi.org/10.1523/JNEUROSCI.3279-05.2005 DO - 10.1523/JNEUROSCI.3279-05.2005 ID - Ramsden2005 ER - TY - JOUR AU - Santacruz, K. AU - Lewis, J. AU - Spires, T. AU - Paulson, J. AU - Kotilinek, L. AU - Ingelsson, M. AU - Guimaraes, A. AU - DeTure, M. AU - Ramsden, M. AU - McGowan, E. PY - 2005 DA - 2005// TI - Tau suppression in a neurodegenerative mouse model improves memory function JO - Science VL - 309 UR - https://doi.org/10.1126/science.1113694 DO - 10.1126/science.1113694 ID - Santacruz2005 ER - TY - JOUR AU - Hunsberger, H. C. AU - Rudy, C. C. AU - Batten, S. R. AU - Gerhardt, G. A. AU - Reed, M. N. PY - 2015 DA - 2015// TI - P301L tau expression affects glutamate release and clearance in the hippocampal trisynaptic pathway JO - J Neurochem VL - 132 UR - https://doi.org/10.1111/jnc.12967 DO - 10.1111/jnc.12967 ID - Hunsberger2015 ER - TY - JOUR AU - Cook, C. AU - Dunmore, J. H. AU - Murray, M. E. AU - Scheffel, K. AU - Shukoor, N. AU - Tong, J. AU - Castanedes-Casey, M. AU - Phillips, V. AU - Rousseau, L. AU - Penuliar, M. S. PY - 2014 DA - 2014// TI - Severe amygdala dysfunction in a MAPT transgenic mouse model of frontotemporal dementia JO - Neurobiol Aging VL - 35 UR - https://doi.org/10.1016/j.neurobiolaging.2013.12.023 DO - 10.1016/j.neurobiolaging.2013.12.023 ID - Cook2014 ER - TY - JOUR AU - Guo, H. AU - Lai, L. AU - Butchbach, M. E. AU - Stockinger, M. P. AU - Shan, X. AU - Bishop, G. A. AU - Lin, C. L. PY - 2003 DA - 2003// TI - Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice JO - Hum Mol Genet VL - 12 UR - https://doi.org/10.1093/hmg/ddg267 DO - 10.1093/hmg/ddg267 ID - Guo2003 ER - TY - JOUR AU - Xing, X. AU - Chang, L. C. AU - Kong, Q. AU - Colton, C. K. AU - Lai, L. AU - Glicksman, M. A. AU - Lin, C. L. AU - Cuny, G. D. PY - 2011 DA - 2011// TI - Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators JO - Bioorg Med Chem Lett VL - 21 UR - https://doi.org/10.1016/j.bmcl.2011.08.009 DO - 10.1016/j.bmcl.2011.08.009 ID - Xing2011 ER - TY - JOUR AU - Blackmore, T. AU - Meftah, S. AU - Murray, T. K. AU - Craig, P. J. AU - Blockeel, A. AU - Phillips, K. AU - Eastwood, B. AU - O’Neill, M. J. AU - Marston, H. AU - Ahmed, Z. PY - 2017 DA - 2017// TI - Tracking progressive pathological and functional decline in the rTg4510 mouse model of tauopathy JO - Alzheimers Res Ther VL - 9 UR - https://doi.org/10.1186/s13195-017-0306-2 DO - 10.1186/s13195-017-0306-2 ID - Blackmore2017 ER - TY - JOUR AU - Li, S. AU - Jin, M. AU - Koeglsperger, T. AU - Shepardson, N. E. AU - Shankar, G. M. AU - Selkoe, D. J. PY - 2011 DA - 2011// TI - Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors JO - J Neurosci VL - 31 UR - https://doi.org/10.1523/JNEUROSCI.0203-11.2011 DO - 10.1523/JNEUROSCI.0203-11.2011 ID - Li2011 ER - TY - JOUR AU - Goebel-Goody, S. M. AU - Davies, K. D. AU - Alvestad Linger, R. M. AU - Freund, R. K. AU - Browning, M. D. PY - 2009 DA - 2009// TI - Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices JO - Neuroscience VL - 158 UR - https://doi.org/10.1016/j.neuroscience.2008.11.006 DO - 10.1016/j.neuroscience.2008.11.006 ID - Goebel-Goody2009 ER - TY - JOUR AU - Sahara, N. AU - DeTure, M. AU - Ren, Y. AU - Ebrahim, A. S. AU - Kang, D. AU - Knight, J. AU - Volbracht, C. AU - Pedersen, J. T. AU - Dickson, D. W. AU - Yen, S. H. AU - Lewis, J. PY - 2013 DA - 2013// TI - Characteristics of TBS-extractable hyperphosphorylated tau species: aggregation intermediates in rTg4510 mouse brain JO - J Alzheimers Dis VL - 33 UR - https://doi.org/10.3233/JAD-2012-121093 DO - 10.3233/JAD-2012-121093 ID - Sahara2013 ER - TY - JOUR AU - Kong, Q. AU - Takahashi, K. AU - Schulte, D. AU - Stouffer, N. AU - Lin, Y. AU - Lin, C. L. PY - 2012 DA - 2012// TI - Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus JO - Neurobiol Dis VL - 47 UR - https://doi.org/10.1016/j.nbd.2012.03.032 DO - 10.1016/j.nbd.2012.03.032 ID - Kong2012 ER - TY - JOUR AU - Attar, A. AU - Liu, T. AU - Chan, W. T. AU - Hayes, J. AU - Nejad, M. AU - Lei, K. AU - Bitan, G. PY - 2013 DA - 2013// TI - A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer’s disease JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0080355 DO - 10.1371/journal.pone.0080355 ID - Attar2013 ER - TY - JOUR AU - Butchbach, M. E. AU - Tian, G. AU - Guo, H. AU - Lin, C. L. PY - 2004 DA - 2004// TI - Association of excitatory amino acid transporters, especially EAAT2, with cholesterol-rich lipid raft microdomains: importance for excitatory amino acid transporter localization and function JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M403938200 DO - 10.1074/jbc.M403938200 ID - Butchbach2004 ER - TY - JOUR AU - Tian, G. AU - Kong, Q. AU - Lai, L. AU - Ray-Chaudhury, A. AU - Lin, C. L. PY - 2010 DA - 2010// TI - Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer’s disease JO - J Neurochem VL - 113 UR - https://doi.org/10.1111/j.1471-4159.2010.06661.x DO - 10.1111/j.1471-4159.2010.06661.x ID - Tian2010 ER - TY - JOUR AU - Stambolic, V. AU - Woodgett, J. R. PY - 1994 DA - 1994// TI - Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation JO - Biochem J VL - 303 UR - https://doi.org/10.1042/bj3030701 DO - 10.1042/bj3030701 ID - Stambolic1994 ER - TY - JOUR AU - Llorens-Martin, M. AU - Jurado, J. AU - Hernandez, F. AU - Avila, J. PY - 2014 DA - 2014// TI - GSK-3beta, a pivotal kinase in Alzheimer disease JO - Front Mol Neurosci VL - 7 ID - Llorens-Martin2014 ER - TY - JOUR AU - Spires, T. L. AU - Orne, J. D. AU - SantaCruz, K. AU - Pitstick, R. AU - Carlson, G. A. AU - Ashe, K. H. AU - Hyman, B. T. PY - 2006 DA - 2006// TI - Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy JO - Am J Pathol VL - 168 UR - https://doi.org/10.2353/ajpath.2006.050840 DO - 10.2353/ajpath.2006.050840 ID - Spires2006 ER - TY - JOUR AU - Beurel, E. AU - Grieco, S. F. AU - Jope, R. S. PY - 2015 DA - 2015// TI - Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases JO - Pharmacol Ther VL - 148 UR - https://doi.org/10.1016/j.pharmthera.2014.11.016 DO - 10.1016/j.pharmthera.2014.11.016 ID - Beurel2015 ER - TY - JOUR AU - Noble, W. AU - Hanger, D. P. AU - Miller, C. C. AU - Lovestone, S. PY - 2013 DA - 2013// TI - The importance of tau phosphorylation for neurodegenerative diseases JO - Front Neurol VL - 4 UR - https://doi.org/10.3389/fneur.2013.00083 DO - 10.3389/fneur.2013.00083 ID - Noble2013 ER - TY - JOUR AU - Medina, M. AU - Garrido, J. J. AU - Wandosell, F. G. PY - 2011 DA - 2011// TI - Modulation of GSK-3 as a therapeutic strategy on tau pathologies JO - Front Mol Neurosci VL - 4 UR - https://doi.org/10.3389/fnmol.2011.00024 DO - 10.3389/fnmol.2011.00024 ID - Medina2011 ER - TY - JOUR AU - Alonso Adel, C. AU - Mederlyova, A. AU - Novak, M. AU - Grundke-Iqbal, I. AU - Iqbal, K. PY - 2004 DA - 2004// TI - Promotion of hyperphosphorylation by frontotemporal dementia tau mutations JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M405131200 DO - 10.1074/jbc.M405131200 ID - Alonso Adel2004 ER - TY - JOUR AU - Kisoh, K. AU - Hayashi, H. AU - Itoh, T. AU - Asada, M. AU - Arai, M. AU - Yuan, B. AU - Tanonaka, K. AU - Takagi, N. PY - 2017 DA - 2017// TI - Involvement of GSK-3β phosphorylation through PI3-K/Akt in cerebral ischemia-induced neurogenesis in rats JO - Mol Neurobiol VL - 54 UR - https://doi.org/10.1007/s12035-016-0290-8 DO - 10.1007/s12035-016-0290-8 ID - Kisoh2017 ER - TY - JOUR AU - Moore, S. F. AU - Bosch, M. T. AU - Hunter, R. W. AU - Sakamoto, K. AU - Poole, A. W. AU - Hers, I. PY - 2013 DA - 2013// TI - Dual regulation of glycogen synthase kinase 3 (GSK3)alpha/beta by protein kinase C (PKC)alpha and Akt promotes thrombin-mediated integrin alphaIIbbeta3 activation and granule secretion in platelets JO - J Biol Chem VL - 288 UR - https://doi.org/10.1074/jbc.M112.429936 DO - 10.1074/jbc.M112.429936 ID - Moore2013 ER - TY - JOUR AU - Tsujio, I. AU - Tanaka, T. AU - Kudo, T. AU - Nishikawa, T. AU - Shinozaki, K. AU - Grundke-Iqbal, I. AU - Iqbal, K. AU - Takeda, M. PY - 2000 DA - 2000// TI - Inactivation of glycogen synthase kinase-3 by protein kinase C delta: implications for regulation of tau phosphorylation JO - FEBS Lett VL - 469 UR - https://doi.org/10.1016/S0014-5793(00)01234-5 DO - 10.1016/S0014-5793(00)01234-5 ID - Tsujio2000 ER - TY - JOUR AU - Christian, S. L. AU - Sims, P. V. AU - Gold, M. R. PY - 2002 DA - 2002// TI - The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3 JO - J Immunol VL - 169 UR - https://doi.org/10.4049/jimmunol.169.2.758 DO - 10.4049/jimmunol.169.2.758 ID - Christian2002 ER - TY - JOUR AU - Hunsberger, H. C. AU - Weitzner, D. S. AU - Rudy, C. C. AU - Hickman, J. E. AU - Libell, E. M. AU - Speer, R. R. AU - Gerhardt, G. A. AU - Reed, M. N. PY - 2015 DA - 2015// TI - Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression JO - J Neurochem VL - 135 UR - https://doi.org/10.1111/jnc.13230 DO - 10.1111/jnc.13230 ID - Hunsberger2015 ER -