From: Depression, subjective cognitive decline, and the risk of neurocognitive disorders
Different combinations of presentation | HR (95% CI)a | P value | Median time to MCI and dementia, year (95% CI)b |
---|---|---|---|
No depression or SCD | 1.0 (Ref) | Ref | 12.2 (12.1–12.3) |
Depression only | 1.4 (1.1–1.7) | 0.004 | 12.1 (11.6–12.2) |
SCD only | 2.0 (1.8–2.2) | < 0.001 | 9.8 (9.1–10.2) |
Both depression and SCD | 2.8 (2.4–3.4) | < 0.001 | 7.2 (5.2–9.1) |