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Table 4 Performance of the system using a different number of features evaluated on the interval 3.5 > Δt > 2.5 years

From: Prediction of amyloid pathology in cognitively unimpaired individuals using voxel-wise analysis of longitudinal structural brain MRI

# features (%) AUC (95% CI) Balanced accuracy (95% CI) Accuracy (95% CI) Precision (95% CI) Sensitivity (95% CI) Specificity (95% CI) F score (95% CI)
6 (0.00) 0.78 (0.50–0.99) 0.70 (0.375–0.875) 0.57 (0.20–0.80) 0.33 (0.13–0.50) 0.91 (0.33–1.00) 0.48 (0–0.75) 0.48 (0.19–0.67)
65 (0.01) 0.81 (0.60–0.97) 0.74 (0.478–0.834) 0.63 (0.27–0.73) 0.38 (0.18–0.43) 0.91 (0.33–1.00) 0.56 (0.12–0.75) 0.50 (0.28–0.6)
653 (0.10) 0.85 (0.67–1.0) 0.77 (0.60–0.88) 0.65 (0.53–0.8) 0.37 (0.27–0.50) 0.97 (0.67–1.00) 0.57 (0.42–0.75) 0.53 (0.38–0.67)
1633 (0.25) 0.86 (0.72–1.00) 0.77 (0.67–0.88) 0.65 (0.46–0.8) 0.37 (0.27–0.50) 0.98 (0.67–1.00) 0.53 (0.33–0.75) 0.53 (0.43–0.67)
3266 (0.50) 0.86 (0.71–0.97) 0.77 (0.60–0.88) 0.64 (0.46–0.8) 0.36 (0.26–0.50) 0.97 (0.67–1.00) 0.56 (0.33–0.75) 0.53 (0.38–0.67)
6532 (1.00) 0.87 (0.72–0.97) 0.76 (0.58–0.88) 0.65 (0.53–0.80) 0.36 (0.25–0.50) 0.933 (0.67–1.00) 0.58 (0.42–0.75) 0.52 (0.36–0.67)
13,064 (2.00) 0.86 (0.64–1.00) 0.75 (0.50–0.88) 0.65 (0.46–0.80) 0.36 (0.20–0.50) 0.917 (0.67–1.00) 0.58 (0.33–0.75) 0.51 (0.31–0.67)
32,661 (5.00) 0.80 (0.49–1.00) 0.67 (0.42–0.86) 0.57 (0.40–0.77) 0.30 (0.14–0.47) 0.837 (0.33–1.00) 0.50 (0.33–0.71) 0.44 (0.33–0.71)
65,323 (10.00) 0.77 (0.40–1.00) 0.66 (0.42–0.86) 0.573 (0.4–0.77) 0.298 (0.14–0.47) 0.813 (0.33–1.00) 0.51 (0.33–0.75) 0.43 (0.33–0.75)
  1. Figures in bold represent the maximum for each performance criterion