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Table 1 Demographic characteristics of the samples

From: A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

 

Sample1

Sample2

Sample3

PSEN1 mutation

Non-carrier

Non-carrier

Ala79Val

Gender

Female

Female

Female

Age on set (years)

87

81

76

Age at death (years)

89

82

89

CDR

1

3

3

APOE

ɛ3/ɛ4

ɛ3/ɛ3

ɛ3/ɛ4

PMI

9

17.2

8

Freezer time& (years)

11

22

24

Braak amyloid beta*

C

NA

C

Neuropathology&

AD

AD

AD

  1. &Freezer time: the years that elapsed since the death to snuclRNA-seq library preparation. *C: Stage C (deposition of amyloid in isocortical areas). AD Alzheimer’s disease, NA no data
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Alzheimer's Research & Therapy

ISSN: 1758-9193