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Table 2 Results of the hypoperfusion-related ELISAs carried out in this study

From: Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced cholinergic input to these areas

 

AD with visual hallucinations, n = 23

AD without visual hallucinations, n = 19

Dementia with Lewy bodies, n = 19

Controls, n = 36

Statistical findings

Age as covariate

Statistics with controls with no Psych Hx or CVAs

Mean

SD

Mean

SD

Mean

SD

Mean

SD

VEGF in BA18 (ng/mg)

79.987

98.734

143.059

158.859

164.705

198.983

106.731

129.774

Kwallis, χ2 = 5.872, p = 0.120

 

Kwallis, χ2 = 5.463, p = 0.140

VEGF in BA19 (ng/mg)

136.886

97.292

203.243

143.618

213.453

125.463

186.541

172.574

Kwallis, χ2 = 4.894, p = 0.180

 

Kwallis, χ2 = 6.836, p = 0.077

MAG in BA18 (ÎĽg/mg)

50.359

47.968

48.091

8.147

45.326

15.884

43.788

7.183

Kwallis, χ2 = 7.610, p = 0.055

  

MAG in BA19 (ÎĽg/mg)

72.119

20.574

66.889

17.848

64.974

9.888

72.966

22.934

ANOVA p = 0.529

p = 0.486

 

MAG:PLP1 in BA18

1.587

0.905

1.62

0.784

1.585

0.835

1.154

0.649

ANOVA p = 0.022

p = 0.034

Kwallis, χ2 = 1.396, p = 0.701

MAG:PLP1 in BA19

1.233

0.59

1.038

0.507

1.089

0.614

1.31

0.913

ANOVA p = 0.534

p = 0.541

Kwallis, χ2 = 2.704, p = 0.440

PLP1 in BA18 (ng/ÎĽg)

40.821

40.649

38.583

24.223

36.472

21.212

50.426

26.188

Kwallis, χ2 = 6.357, p = 0.096

  

PLP1 in BA19 (ng/ÎĽg)

69.523

34.204

75.993

36.68

74.969

35.674

74.161

42.655

ANOVA p = 0.920

p = 0.915

 

von Willebrand factor in BA18 (arbitrary units/ÎĽg)

1.713

1.345

1.824

1.246

1.636

0.968

1.568

0.767

ANOVA p = 0.864

p = 0.842

Kwallis, χ2 = 4.580, p = 0.205

von Willebrand factor in BA19 (arbitrary units/ÎĽg)

2.267

0.832

2.26

0.896

1.94

0.653

1.909

1.234

Kwallis, χ2 = 8.223, p = 0.042

 

Kwallis, χ2 = 5.916, p = 0.116