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Table 2 Correlations between [18F]flortaucipir BPND and regional GM density in the total group, cognitively normal individuals and MCI/AD

From: Associations between quantitative [18F]flortaucipir tau PET and atrophy across the Alzheimer’s disease spectrum

  Entorhinal cortex Hippocampus Medial temporal Lateral temporal Medial parietal Lateral parietal Occipital Frontal Global
Total group
 [18F]Flortaucipir BPND entorhinal cortex − 0.422**# − 0.505**# − 0.491**# − 0.424**# − 0.362**# − 0.358**# − 0.392**# − 0.335**# − 0.377**#
 [18F]Flortaucipir BPND in ROI Braak III–IV − 0.410**# − 0.439**# − 0.439**# − 0.598**# − 0.493**# − 0.475**# − 0.552**# − 0.378**# − 0.472**#
 [18F]Flortaucipir BPND in ROI Braak V–VI − 0.344**# − 0.393**# − 0.385**# − 0.592**# − 0.548**# − 0.546**# − 0.627**# − 0.405**# − 0.499**#
Cognitively normal
 [18F]Flortaucipir BPND entorhinal cortex 0.004 − 0.090 − 0.080 − 0.087 − 0.116 − 0.027 − 0.129 − 0.198 − 0.114
 [18F]Flortaucipir BPND in ROI Braak III–IV − 0.087 − 0.070 − 0.089 − 0.120 − 0.190 − 0.048 − 0.015 − 0.033 − 0.079
 [18F]Flortaucipir BPND in ROI Braak V–VI − 0.057 − 0.053 − 0.068 − 0.137 − 0.229 − 0.122 − 0.064 − 0.130 − 0.099
MCI/AD
 [18F]Flortaucipir BPND entorhinal cortex − 0.378**# − 0.422**# − 0.404**# − 0.226* − 0.116 − 0.132 − 0.114 − 0.210* − 0.211*
 [18F]Flortaucipir BPND in ROI Braak III–IV − 0.256* − 0.209 − 0.224 − 0.555**# − 0.350**# − 0.348**# − 0.432**# − 0.299**# − 0.393**#
 [18F]Flortaucipir BPND in ROI Braak V–VI − 0.132 − 0.119 − 0.123 − 0.529**# − 0.451**# − 0.460**# − 0.548**# − 0.329**# − 0.431**#
  1. *p < 0.05, **p < 0.01, #FDR corrected