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Table 3 List of variables used to construct the 50-item frailty index

From: Frailty effects on non-demented cognitive trajectories are moderated by sex and Alzheimer’s genetic risk

  Frailty measures Coding
SR Stroke 0 = no; 0.33 = yes, not serious; 0.67 = yes, moderately serious; 1 = yes, very serious
Thyroid condition
Arthritis (rheumatoid and/or osteo-)
Osteoporosis
Cancer
Asthma
Migraines
Stomach ulcer
Kidney or bladder trouble
Gastrointestinal problems (colitis/diverticulitis, gall bladder trouble, and/or liver trouble)
Bronchitis or emphysema
Diabetes
High blood pressure
Sex-related health problems (i.e., gynecological problems or prostate problems)
Anemia
Drug and/or alcohol dependence
Spinal condition and/or back trouble
Hardening of arteries (i.e., atherosclerosis)
Heart trouble
Other conditions (up to three)
SR Number of medications 0 = 0–3; 0.5 = 4–7; 1 = 8+
SR Subjective health relative to a perfect state of health 0 = very good; 0.25 = good; 0.50 = fair; 0.75 = poor; 1 = very poor
Eyesight relative to age group
Hearing relative to age group
SR Health has affected ability to do chores 0 = no change, improved, N/A; 0.25 = slightly reduced; 0.50 = moderately reduced; 0.75 = drastically reduced; 1 = gave up doing activity
Health has affected ability to get around town
Health has affected ability to do mental recreational activities
Health has affected ability to do physical recreational activities
Health has affected ability to do hobbies
Health has affected ability to socialize
Health has affected ability to travel
SR Stay at home but in chair most of the time 0 = no; 1 = yes
SR Number of times sick in bed all day in the past year 0 = 0–3; 1 = 4+
SR Number of timse confined to hospital in the past year 0 = 0; 0.5 = 1–2; 3+ = 1
SR Feeling short of breath 0 = no; 1 = yes
SR Use of a walker, cane, or wheelchair 0 = no; 1 = yes
M Resting heart rate (bpm) 0 = 60–99; 1 = < 60 or 100+
M Pulse pressure (mmHg) 0 = 32.13–63.90; 0.5 = 64–75.9; 1 = 76+
M Peak expiratory flow (L/min) Men: 0 = > 340, 1 = ≤ 340 Women: 0 = > 310, 1 = ≤ 310
M Body mass index (kg/m2) 0 = 18.5–25; 0.5 = 25 to < 30; 1 = < 18.5 or ≥ 30
M Grip strength (kg) Men: for BMI ≤ 24, GS ≤ 29; for BMI 24.1–28, GS ≤ 30; for BMI > 28, GS ≤ 32 Women: for BMI ≤ 23, GS ≤ 17; for BMI 23.1–26, GS ≤ 17.3; for BMI 26.1–29, GS ≤ 18; for BMI > 29, GS ≤ 21
M Timed walk 0 = ≤ 10 s; 1 = > 10 s
M Timed turn 0 = < 90th percentile; 1 = within the 90th percentile
M Finger dexterity 0 = < 90th percentile; 1 = within the 90th percentile
SR CES-D “during the past week, my sleep was restless” 0 = rarely or none of the time; 0.33 = some or a little of the time; 0.67 = occasionally or a moderate amount of the time; 1 = most or all of the time
SR CES-D “during the past week, I felt depressed”
SR CES-D “during the past week, I felt lonely”
SR CES-D “during the past week, I could not get going”
SR Bradburn negative affect (restless, lonely, bored, depressed, upset due to criticism) 0 = no to all; 0.2 = yes to one; 0.4 = yes to two; 0.6 = yes to three; 0.8 = yes to four; 1 = yes to all
SR Physical activity at least 2–3 times per week 0 = yes; 1 = no
  1. SR self-reported, M measured, CES-D Center for Epidemiological Studies Depression Scale