Anxiety correlates with cortical surface area in subjective cognitive decline: APOE ε4 carriers versus APOE ε4 non-carriers

Table 3 The estimated value of interaction effect between APOE and diagnosis in cortical morphometric features

	Groups	APOE	Estimation	95%CI	P value
Cortex volume	SCD	ε4 +	397.829 ± 8.076	381.848–413.810	.25
	SCD	ε4 −	416.300 ± 4.579	407.203–425.398
	NC	ε4 +	420.606 ± 8.562	403.664–437.548
	NC	ε4 −	423.750 ± 4.312	415.217–432.283
Surface area in right hemisphere	SCD	ε4 +	742.296 ± 13.860	714.871–769.722	.086
	SCD	ε4 −	782.810 ± 7.890	767.197–798.423
	NC	ε4 +	794.782 ± 14.694	765.706–823.857
	NC	ε4 −	795.956 ± 7.400	781.312–810.600
Surface area in left hemisphere	SCD	ε4 +	741.824 ± 15.268	711.613–772.036	.118
	SCD	ε4 −	786.760 ± 8.691	769.561–803.959
	NC	ε4 +	795.066 ± 16.186	763.037–827.096
	NC	ε4 −	800.473 ± 8.152	784.342–816.605
Thickness in right hemisphere	SCD	ε4 +	2.402 ± 0.020	2.362–2.442	.495
	SCD	ε4 −	2.381 ± 0.011	2.358–2.404
	NC	ε4 +	2.378 ± 0.021	2.336–2.421
	NC	ε4 −	2.380 ± 0.011	2.359–2.401
Thickness in left hemisphere	SCD	ε4 +	2.406 ± 0.021	2.365–2.447	.246
	SCD	ε4 −	2.374 ± 0.012	2.350–2.397
	NC	ε4 +	2.381 ± 0.022	2.337–2.425
	NC	ε4 −	2.389 ± 0.011	2.367–2.411

Data is expressed as the means ± SD; 95%CI, 95% confidence interval; covariates include age, gender, and year of education; ε4 + was APOE ε4 carriers while ε4 – was non-carriers

ISSN: 1758-9193