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Table 1 Relevant demographic and clinical variables in the sample

From: Electrophysiological brain signatures for the classification of subjective cognitive decline: towards an individual detection in the preclinical stages of dementia

 

Mean ± SD

p values

HC

SCD

MCI

HC vs SCD

Age

70.6 (4.4)

72.3 (5.2)

72.8 (4)

0.031

Gender (M-F)

29–41

20–71

35–56

0.008*

APOE (pos-neg)

15–49

16–65

36–51

0.59

GDS

1.4 (1.8)

3.0 (3.3)

3.7 (3.0)

0.001*

MMSE (gral. cognition)

28.9 (1.2)

28.2 (1.8)

26.9 (2.3)

0.104

RBMT global (episodic memory)

10.0 (1.6)

9.3 (2.4)

5.8 (3.2)

0.13

Direct digit (working memory)

8.5 (2)

8.4 (1.9)

7 (2.1)

0.660

Inverse digit (working memory)

6.2 (1.8)

5.2 (1.8)

4.2 (1.4)

0.009*

TMTA (hits) (executive funct.)

23.9 (0.3)

23.9 (0.5)

23.9 (0.9)

0.866

TMTB (hits) (executive funct.)

23.2 (2.5)

22.4 (3.1)

19.1 (6.1)

0.211

Gesture imitation (Praxis)

7.8 (0.6)

7.5 (0.9)

7.1 (1.3)

0.184

7 M-fluency (language)

20.5 (4.7)

18.6 (4.8)

13.7 (3.9)

0.140

7 M-clock (Praxis)

6.7 (0.5)

6.4 (1.1)

5.9 (1.4)

0.084

  1. Age is compared using independent samples t test. Gender and APOE status (expressed as presence–absence of APOE4 allele) are compared using chi-squared. Neuropsychological test contrasts are adjusted by age and education. Each test is followed by the main cognitive domain intended to measure
  2. *p < 0.05