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Table 1 Relevant demographic and clinical variables in the sample

From: Electrophysiological brain signatures for the classification of subjective cognitive decline: towards an individual detection in the preclinical stages of dementia

  Mean ± SD p values
HC SCD MCI HC vs SCD
Age 70.6 (4.4) 72.3 (5.2) 72.8 (4) 0.031
Gender (M-F) 29–41 20–71 35–56 0.008*
APOE (pos-neg) 15–49 16–65 36–51 0.59
GDS 1.4 (1.8) 3.0 (3.3) 3.7 (3.0) 0.001*
MMSE (gral. cognition) 28.9 (1.2) 28.2 (1.8) 26.9 (2.3) 0.104
RBMT global (episodic memory) 10.0 (1.6) 9.3 (2.4) 5.8 (3.2) 0.13
Direct digit (working memory) 8.5 (2) 8.4 (1.9) 7 (2.1) 0.660
Inverse digit (working memory) 6.2 (1.8) 5.2 (1.8) 4.2 (1.4) 0.009*
TMTA (hits) (executive funct.) 23.9 (0.3) 23.9 (0.5) 23.9 (0.9) 0.866
TMTB (hits) (executive funct.) 23.2 (2.5) 22.4 (3.1) 19.1 (6.1) 0.211
Gesture imitation (Praxis) 7.8 (0.6) 7.5 (0.9) 7.1 (1.3) 0.184
7 M-fluency (language) 20.5 (4.7) 18.6 (4.8) 13.7 (3.9) 0.140
7 M-clock (Praxis) 6.7 (0.5) 6.4 (1.1) 5.9 (1.4) 0.084
  1. Age is compared using independent samples t test. Gender and APOE status (expressed as presence–absence of APOE4 allele) are compared using chi-squared. Neuropsychological test contrasts are adjusted by age and education. Each test is followed by the main cognitive domain intended to measure
  2. *p < 0.05