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Table 2 Individual and signature miRNAs performance characteristics in predicting MCI stage. Signature miRNA performance characteristics in women and men

From: Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer’s disease

miRNA/signature AUC Sensitivity % Specificity % Youden Index J P value
miR-92a-3p 0.673 50.00 92.86 0.428 0.0563
miR-181c-5p 0.843 84.62 85.71 0.703 < 0.0001
miR-210-3p 0.736 76.92 71.43 0.483 0.0038
miR-92a-3p/miR-210-3p 0.731 73.08 71.43 0.445 0.0050
miR-92a-3p/miR-181c-5p 0.838 84.62 78.57 0.632 < 0.0001
miR-181c-5p/miR-210-3p 0.865 88.46 78.57 0.670 < 0.0001
miR-92a-3p/miR-181c-5p/ miR-210-3p 0.893 84.62 85.71 0.703 < 0.0001
Women 0.821 87.50 71.43 0.589 0.0005
Men 0.957 100.0 85.71 0.857 < 0.0001
  1. AUC area under the curve