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Table 1 Descriptive characteristics and test scores separately for each diagnostic group

From: Assessing cognition and daily function in early dementia using the cognitive-functional composite: findings from the Catch-Cog study cohort

  SCD (n = 14) MCI (n = 80) AD (n = 78) DLB (n = 12) p value Post hoc between group comparisons*
Descriptives
 Age 68.1 (6.6) 73.6 (8.0) 71.3 (9.1) 68.3 (6.1) .033 Non-significant
 Female (%) 8 (57.1%) 29 (36.3%) 39 (50%) 2 (16.7%) .060 N.A.
 Education 15.2 (4.8) 13.7 (3.6) 13.2 (4.0) 13.6 (3.3) .36 N.A.
 MMSE 29.3 (1.2) 26.7 (2.3) 24.0 (3.3) 24.4 (2.9) < .001 SCD > MCI > AD; SCD >DLB
CFC components
 Cognitive composite .88 (.50) .19 (.50) − .31 (.61) − .35 (.71) < .001 SCD > MCI > AD, SCD > DLB, MCI > DLB
 A-IADL-Q .91 (.79) .39 (.73) − .48 (.84) − .65 (.90) < .001 SCD > AD; MCI < AD; SCD > DLB; MCI > DLB
 CFC score .89 (.57) .29 (.51) − .39 (.61) − .51 (.75) < .001 SCD > MCI > AD; SCD > DLB; MCI > DLB
Reference measures
 CFI-SP N.A. 6.9 (3.2) 4.9 (2.8) N.A. < .001 N.A.
 QoL-AD N.A. 33.8 (5.3) 31.6 (5.2) N.A. .026 N.A.
 ZBI-12 N.A. 10.7 (7.7) 14.4 (7.9) N.A. .004 N.A.
 AES N.A. 39.9 (10.5) 43.3 (10.0) N.A. .053 N.A.
Traditional tests
 ADAS-Cog N.A. 22.2 (6.8) 28.5 (7.6) N.A. < .001 N.A.
 ADCS-ADL N.A. 67.5 (7.8) 63.7 (8.8) N.A. .010 N.A.
 CDR-SB N.A. 2.7 (1.9) 5.1 (2.2) N.A. < .001 N.A.
  1. Abbreviations: ADAS-Cog Alzheimer’s Disease Assessment Scale–Cognitive subscale, ADCS-ADL Alzheimer’s Disease Cooperation Study–Activity of Daily Living, AES Apathy Evaluation Scale, A-IADL-Q Amsterdam IADL Questionnaire, CDR-SB Clinical Dementia Rating Sum of Boxes, CFC cognitive-functional composite, CFI-SP Cognitive Function Instrument study partner version, MMSE Mini-Mental State Examination, QoL Quality of life, ZBI Zarit Burden Inventory
  2. *Based on Hochberg’s post hoc tests