Variables | Group 1, 15 mg (n = 51) | Group 2, 10/23 mg (n = 55) | Group 3, no titration (n = 54) | p value |
---|---|---|---|---|
Anorexia | 9/51, 17.6% | 12/55, 21.8% | 12/54, 22.2% | 0.815 |
Dizziness* | 4/51, 7.8% | 4/55, 7.3% | 12/54, 22.2% | 0.029 |
Nausea* | 4/51, 7.8% | 5/55, 9.1% | 13/54, 24.1% | 0.025 |
Vomiting | 4/51, 7.8% | 7/55, 12.7% | 9/54, 16.7% | 0.392 |
Generalized weakness | 4/51, 7.8% | 8/55, 14.5% | 5/54, 9.3% | 0.494 |
Weight loss | 4/51, 7.8% | 4/55, 7.3% | 3/54, 5.6% | 0.928 |
Diarrhea | 2/51, 3.9% | 4/55, 7.3% | 5/54, 9.3% | 0.584 |
Dyspepsia | 0/51, 0% | 4/55, 7.3% | 3/54, 5.6% | 0.179 |
Urinary frequency | 2/51, 3.9% | 4/55, 7.3% | 0/54, 0% | 0.122 |
Increased neuropsychiatric sx. | 0/51, 0% | 1/55, 1.8% | 1/54, 1.9% | 1.000 |
Insomnia | 1/51, 2.0% | 2/55, 3.6% | 0/54, 0% | 0.537 |
Headache | 0/51, 0% | 0/55, 0% | 3/54, 5.6% | 0.068 |
Tremor | 1/51, 2.0% | 1/55, 1.8% | 1/54, 1.9% | 1.000 |
Cold sweating | 0/51, 0% | 1/55, 1.8% | 0/54, 0% | 1.000 |
Drooling | 0/51, 0% | 1/55, 1.8% | 1/54, 1.9% | 1.000 |
Abdominal pain | 1/51, 2.0% | 0/55, 0% | 0/54, 0% | 0.319 |
Unexpected nocturnal ejaculation | 0/51, 0% | 0/55, 0% | 1/54, 1.9% | 1.000 |
Heartburn | 0/51, 0% | 0/55, 0% | 1/54, 1.9% | 1.000 |
PISA syndrome | 1/51, 2.0% | 0/55, 0% | 0/54, 0% | 0.319 |
High BP | 0/51, 0% | 0/55, 0% | 1/54, 1.9% | 1.000 |
Fecal incontinence | 0/51, 0% | 0/55, 0% | 1/54, 1.9% | 1.000 |