Fig. 5

Correlation between the binding levels of TSPO and SERT. Pearson’s product moment correlation was employed to examine the relationship between the binding levels of TSPO and SERT. Age-dependent increases in the binding of [³H]PK11195 were inversely correlated with SERT density in the parietal, but not the frontal, occipital, and temporal cortices of APP_swe/PS1_dE9 mice. Each data point represents binding of [³H]PK11195 and [³H]DASB in a single animal