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Table 2 Regression coefficient of the final model

From: Personalized risk for clinical progression in cognitively normal subjects—the ABIDE project

  MCI/dementia MCI/AD-dementia
Coëfficient Standard error p value Harrell’s C Coëfficient Standard Error p value Harrell’s C
Demographic (n = 481)
 Age 0.0854 0.0147 < .001 0.70 0.0904 0.0162 < .001 0.70
 MMSE − 0.2497 0.0639 < .001 − 0.2236 0.0726 < .01  
CSF (n = 344)
 Aβ − 1.0462 0.3668 < .01 0.82 − 1.3941 0.4031 < .01 0.84
 Tau 1.2785 0.3384 < .001 1.3829 0.4003 < .01
 Age 0.0704 0.0251 < .01 0.0644 0.0296 < .05
 Gender − 0.6360 0.3345 < .10 − 0.6375 0.3814 < .10
 MMSE − 0.25503 0.0815 < .01 − 0.1846 0.0981 < .10
 Tau* age − 0.1393 0.0467 < .01 − 0.1311 0.0534 < .05
  1. CSF biomarkers (Aβ and Tau) are log-transformed and centered. MMSE mini-mental state examination, Tau* age interaction between age and Tau. Interaction term was centered and standardized to allow inclusion in the model