Skip to main content

Table 2 Regression coefficient of the final model

From: Personalized risk for clinical progression in cognitively normal subjects—the ABIDE project

 

MCI/dementia

MCI/AD-dementia

Coëfficient

Standard error

p value

Harrell’s C

Coëfficient

Standard Error

p value

Harrell’s C

Demographic (n = 481)

 Age

0.0854

0.0147

< .001

0.70

0.0904

0.0162

< .001

0.70

 MMSE

− 0.2497

0.0639

< .001

− 0.2236

0.0726

< .01

 

CSF (n = 344)

 Aβ

− 1.0462

0.3668

< .01

0.82

− 1.3941

0.4031

< .01

0.84

 Tau

1.2785

0.3384

< .001

1.3829

0.4003

< .01

 Age

0.0704

0.0251

< .01

0.0644

0.0296

< .05

 Gender

− 0.6360

0.3345

< .10

− 0.6375

0.3814

< .10

 MMSE

− 0.25503

0.0815

< .01

− 0.1846

0.0981

< .10

 Tau* age

− 0.1393

0.0467

< .01

− 0.1311

0.0534

< .05

  1. CSF biomarkers (Aβ and Tau) are log-transformed and centered. MMSE mini-mental state examination, Tau* age interaction between age and Tau. Interaction term was centered and standardized to allow inclusion in the model
Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193