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Table 1 Comparison between AD patients (A+T+N+ classification) who were included and not included in the analyses due to missing data

From: CSF level of β-amyloid peptide predicts mortality in Alzheimer’s disease

Characteristics

AD patients with A+T+N+ profile

Included

Not included

 

(N = 321)

(N = 61)

P value

Age, year, mean (SD)

71.0 (8.5)

71.3 (8.1)

0.68

Women, n (%)

200 (62.3)

37 (59.7)

0.70

MMSE, mean (SD)

20.3 (5.8)

20.3 (6.7)

0.85

Level of education, n (%)a

 Low

106 (35.8)

15 (31.9)

 

 Intermediate

110 (36.8)

11 (23.4)

 

 High

81 (27.4)

21 (44.7)

0.04

CSF biomarkers, pg/mL, mean (SD)

 Aβ42

483.8 (134.8)

471.8 (133.7)

0.52

 Aβ40b

13,345 (5447)

13,323 (4812)

0.92

 Ratio Aβ42/40b

0.047 (0.022)

0.044 (0.017)

0.57

 Tau

684.9 (276.9)

671.8 (285.9)

0.72

 p-Tau 181

102.6 (39.0)

100.9 (39.5)

0.73

  1. A+T+N+ profile: Abnormal values for three CSF biomarkers (Aβ42, total tau, phosphorylated tau (p-tau 181))
  2. AD Alzheimer’s disease, SD standard deviation
  3. aLow: primary school or less, intermediate: secondary to high school, high: baccalaureate or university degree
  4. bCSF Aβ40 was available for 255 patients