Lesion co-morbidity index
|
OR for the Nun Study (n = 334)
|
OR for the Honolulu Asia Aging Study (n = 774)
|
---|
0
|
1.0 (reference)
|
1.0 (reference)
|
0.4–0.8
|
2.8
|
2.4
|
1.0–1.8
|
5.0
|
4.6
|
2.0–2.4
|
23.1
|
16.3
|
2.6–4.4
|
99.1
|
37.6
|
- Severity of each of the five brain lesions (Braak stage for neurofibrillary degeneration, cerebral cortical Lewy body disease, cerebral cortical microinfarcts, hippocampal sclerosis, low brain weight) was scored as none/mild (0), moderate (0.4), or severe (1.0) by established criteria, and the lesion co-morbidity index was calculated as the sum of scores for each of the five lesions [1]