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Table 11 Overview of the psychometric properties for computer tests

From: Brief cognitive screening instruments for early detection of Alzheimer’s disease: a systematic review

Instrument Number of articles* N
healthy controls
N
MCI/AD
n Sensitivity Specificity n AUC n Internal consistency n Inter-rater reliability n Test-retest reliability (mean time between tests)
Test validated for MCI in a (memory) clinic
 Cogstate 1 653 107 760 80.4 84.7 760 91.0       
 CANTAB-PAL 1 22 17 39    39 80.3       
 CANS-MCI 2 61 50 111 83.5 73.0 111 82.1 97 0.77    97 0.88 (3 months)
 MoCA computer tool (MoCA-CC) 1 85 96 781 95.8 87.1 781 97.0       0.82 (6 weeks)
Test validated for MCI in a population-based cohort
 CAMCI 1 296 228 524 86 94.0    524 0.72     
Tests validated for AD in a (memory) clinic
 Cogstate 1 653 44 697 100.0 84.7 653 99.0      697 0.70 (4 months)
 CANTAB-PAL 1 16 34 50 68.0 98.0         
 CANS-MCI 1 41 21 62 100.0 97.0 62 98.0 97 0.77    97 0.88 (3 months)
 Test Inoue 1 102 72 174 96.0 86.0         
  1. *When more than 1 study is available, the weighted mean is calculated for the sensitivity, specificity, AUC, internal consistency, inter-rater reliability, and test-retest reliability
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