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Table 4 Prevalence and performance of selected hypometabolism hallmarks in discriminating DLB from ADD and PD patients

From: Brain glucose metabolism in Lewy body dementia: implications for diagnostic criteria

Prevalence (%) of selected hypometabolism hallmarks
  Occipital hypometabolism Cingulate island sign DLPFC hypometabolism Hypometabolism symmetry
DLB 66/72 (91.7%) 57/72 (79.2%) 31/72 (43.1%) 71/72 (98.6%)
ADD 5/60 (8.3%) 22/60 (36.7%) 10/60 (16.7%) 47/60 (78.3%)
PD 5/36 (13.9%) 2/36 (5.56%)
Performance of selected hypometabolism hallmarks
  DLB vs. ADD
Hypometabolism hallmarks Sensitivity Specificity Accuracy
Occipital hypometabolism 0.92 (0.83–0.97) 0.92 (0.82–0.97) 0.92 (0.86–0.96)
Cingulate island sign 0.79 (0.68–0.88) 0.63 (0.50–0.75) 0.72 (0.63–0.79)
DLPFC hypometabolism 0.43 (0.31–0.55) 0.83 (0.71–0.92) 0.61 (0.53–0.70)
Hypometabolism symmetry 0.99 (0.93–1) 0.22 (0.12–0.34) 0.64 (0.55–0.72)
  DLB vs. PD
Hypometabolism hallmarks Sensitivity Specificity Accuracy
Occipital hypometabolism 0.92 (0.83–0.97) 0.86 (0.70–0.95) 0.90 (0.83–0.95)
Cingulate island sign
DLPFC hypometabolism 0.43 (0.31–0.55) 0.94 (0.81–0.99) 0.60 (0.50–0.69)
Hypometabolism symmetry
  1. Abbreviations: ADD Alzheimer’s disease dementia, DLB dementia with Lewy bodies, DLPFC dorsolateral prefrontal cortex, PD Parkinson’s disease