Table 4 Prevalence and performance of selected hypometabolism hallmarks in discriminating DLB from ADD and PD patients
From: Brain glucose metabolism in Lewy body dementia: implications for diagnostic criteria
Prevalence (%) of selected hypometabolism hallmarks | ||||
| Â | Occipital hypometabolism | Cingulate island sign | DLPFC hypometabolism | Hypometabolism symmetry |
DLB | 66/72 (91.7%) | 57/72 (79.2%) | 31/72 (43.1%) | 71/72 (98.6%) |
ADD | 5/60 (8.3%) | 22/60 (36.7%) | 10/60 (16.7%) | 47/60 (78.3%) |
PD | 5/36 (13.9%) | – | 2/36 (5.56%) | – |
Performance of selected hypometabolism hallmarks | ||||
| Â | DLB vs. ADD | |||
Hypometabolism hallmarks | Sensitivity | Specificity | Accuracy | |
Occipital hypometabolism | 0.92 (0.83–0.97) | 0.92 (0.82–0.97) | 0.92 (0.86–0.96) | |
Cingulate island sign | 0.79 (0.68–0.88) | 0.63 (0.50–0.75) | 0.72 (0.63–0.79) | |
DLPFC hypometabolism | 0.43 (0.31–0.55) | 0.83 (0.71–0.92) | 0.61 (0.53–0.70) | |
Hypometabolism symmetry | 0.99 (0.93–1) | 0.22 (0.12–0.34) | 0.64 (0.55–0.72) | |
| Â | DLB vs. PD | |||
Hypometabolism hallmarks | Sensitivity | Specificity | Accuracy | |
Occipital hypometabolism | 0.92 (0.83–0.97) | 0.86 (0.70–0.95) | 0.90 (0.83–0.95) | |
Cingulate island sign | – | – | – | |
DLPFC hypometabolism | 0.43 (0.31–0.55) | 0.94 (0.81–0.99) | 0.60 (0.50–0.69) | |
Hypometabolism symmetry | – | – | – | |