Table 1 Demographics and clinical features of the case series at entry and follow-up
From: Brain glucose metabolism in Lewy body dementia: implications for diagnostic criteria
Clinical classification at entry | Possible DLB | Probable DLB | Atypical parkinsonism | MCI | Other dementias |
N | 10 | 34 | 5 | 15 | 8 |
Gender (M/F) | 4/6 | 21/13 | 3/2 | 10/5 | 4/4 |
Age at PET scan (years) | 70.40 ± 7.93 (59–81) | 74.56 ± 7.94 (48–93) | 68.20 ± 8.08 (57–77) | 68.80 ± 5.47 (58–78) | 75.00 ± 6.14 (68–88) |
MMSE score at entry | 19.11 ± 3.68 (14–24) | 17.87 ± 5.21 (7.70–26.70) | 18.76 ± 2–20 (15.60–20.30) | 22.20 ± 2.86 (18.9–27) | 13.36 ± 2.06 (10–15.3) |
Disease duration at entry (years) | 3.68 ± 2.75 (1.00–10.75) | 2.38 ± 1.53 (0.20–6.00) | 2.30 ± 2.09 (0.30–5.50) | 1.23 ± 0.83 (0.33–2.90) | 3.59 ± 2.07 (0.20–7.00) |
Time of follow-up (years) | 2.70 ± 1.63 (0.34–4.36) | 3.09 ± 1.46 (0.77–6.04) | 3.71 ± 1.29 (2.92–5.20) | 2.89 ± 0.32 (0.78–4.93) | 1.41 ± 0.39 (1.16–1.86) |
Visual hallucinations (%) | 30% | 53% | 40% | 53% | 63% |
Cognitive fluctuations (%) | 0% | 35% | 20% | 27% | 38% |
Parkinsonism (%) | 100% | 94% | 100% | 67% | 75% |
aClinical classification at follow-up | Probable DLB | Probable DLB | Probable DLB | Probable DLB | Probable DLB |
Visual hallucinations (%) | 90% | 74% | 80% | 67% | 88% |
Cognitive fluctuations (%) | 70% | 82% | 60% | 53% | 63% |
Parkinsonism (%) | 100% | 100% | 100% | 80% | 75% |
RBD (%) | 40% | 62% | 20% | 40% | 38% |
Neuroleptic sensitivity (%) | 10% | 6% | 0% | 0% | 0% |
Available DATSCAN (N) | 3 out of 10 (positive) | 7 out of 34 (positive) | 3 out of 5 (positive) | 1 out of 15 (positive) | 0 out of 8 |