Fig. 4
From: 18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes
18F-flortaucipir in bvFTD. a Five bvFTD scans and corresponding single-subject w-score maps determined to have clear uptake signal in frontal and temporal lobes. Patient 1 is a 46-year-old male, MMSE 22, CDR-SB 4, PiB negative. Patient 2 is a 54-year-old female, MMSE 19, CDR-SB 5, PiB negative. Patient 3 is a 74-year-old male with MMSE 23, CDR-SB 7.5, PiB positive. Patient 4 is a 69-year-old male, MMSE 22, CDR-SB 9, PiB positive. Patient 5 is a 78-year-old female, MMSE 18, CDR-SB 12, PiB positive. b Five bvFTD scans and corresponding single-subject w-score maps determined to have minimal or no uptake in frontal and temporal lobes. Patient 6 is a 76-year-old male, MMSE 26, CDR-SB 6.5, PiB negative. Patient 7 is a 74-year-old male, MMSE 26, CDR-SB 1.5, PiB negative. Patient 8 is a 64-year-old male, MMSE 27, CDR-SB 7.5, PiB negative. Patient 9 is a 68-year-old male, MMSE 29, CDR-SB 5, PiB negative. Patient 10 is a 34-year-old male, MMSE 22, CDR-SB 8, Aβ status unavailable. c 18F-flortaucipir SUVR values for each pre-specified region of interest; horizontal bar denotes mean. L, left; NC, normal control