Fig. 2
From: 18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes
18F-flortaucipir in CBS. a CBS-flortaucipir (+) example is a 71-year-old female patient, MMSE 29, CDR-SB 2.5, PiB positive. CBS-flortaucipir (−) example is a 60-year-old male patient, MMSE 26, CDR 1.5 PiB negative. CBS-AD example is a 70-year-old male patient, MMSE 25, CDR-SB 7, PiB positive. b Voxel-wise contrast of 18F-flortaucipir images in seven CBS patients (without CBS-AD images) with 53 normal controls with age as covariate. c W-score frequency map showing number of patients with suprathreshold age-adjusted SUVR values (w-score ≥ 1.65) compared to normal controls. Peak voxels suggest four of seven subjects have elevated w-score voxels in the same region. d 18F-flortaucipir SUVR values for each pre-specified region of interest; horizontal bar denotes mean. NC, normal control; CL, contralateral to symptom onset; IL, ipsilateral to symptom onset; CMF, caudal middle frontal; WM, white matter