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Fig. 7 | Alzheimer's Research & Therapy

Fig. 7

From: CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice

Fig. 7

Quantification of non-activated microglia at fear and spatial memory-related regions. Because microglia in grey matter regions appear as either a non-activated ramified morphology with a size of less than 145 μm2 or an activated morphology with a size greater than 145 μm2, the 145-μm2 size was used as a surrogate cut-off for non-activated and activated microglia. The density and stain area for each type of microglia are plotted for (a, b) prefrontal cortex, (c, d) amygdala, and (e, f) hippocampus. Data are shown as mean ± SE with an overlaid scatterplot of individual animals. Asterisks indicate significant post hoc difference between APP/PS1-TBI and APP/PS1-Sham (* p < 0.05; ** p < 0.01)

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