From: Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study
Predictors | AUC [95% CI] | Sensitivity [95% CI] | Specificity [95% CI] |
---|---|---|---|
Entire modela | 0.73 [0.68–0.78] | 0.66 [0.63–0.69] | 0.68 [0.66–0.71] |
Cognitionb | 0.72 [0.66–0.78] | 0.55 [0.51–0.59] | 0.55 [0.52–0.58] |
MMSE Calculationc | 0.60 [0.53–0.68] | 0.53 [0.49–0.56] | 0.68 [0.66–0.70] |
MMSE Orientationc | 0.64 [0.58–0.70] | 0.68 [0.65–0.71] | 0.54 [0.51–0.56] |
MMSE Other tasksc | 0.65 [0.58–0.72] | 0.56 [0.53–0.58] | 0.67 [0.65–0.69] |
MMSE Wordlistc | 0.68 [0.62–0.75] | 0.77 [0.75–0.80] | 0.57 [0.55–0.60] |
SPMSQc | 0.71 [0.65–0.77] | 0.67 [0.65–0.70] | 0.64 [0.62–0.67] |
MMSE totalc | 0.71 [0.64–0.77] | 0.62 [0.59–0.65] | 0.61 [0.58–0.63] |
Functioningb | 0.61 [0.55–0.67] | 0.62 [0.59–0.65] | 0.61 [0.58–0.63] |
Competence in daily activitiesc | 0.61 [0.55–0.67] | 0.83 [0.81–0.86] | 0.35 [0.32–0.38] |
Sociodemographicsb | 0.60 [0.54–0.65] | 0.83 [0.81–0.86] | 0.35 [0.32–0.38] |
Education, yearsc | 0.60 [0.54–0.65] | 0.66 [0.63–0.69] | 0.68 [0.66–0.71] |
APOE genotypeb | 0.58 [0.52–0.64] | 0.45 [0.42–0.47] | 0.69 [0.67–0.71] |
APOEε2 carriersc | 0.56 [0.51–0.61] | 0.25 [0.23–0.27] | 0.88 [0.86–0.89] |
APOEε3ε3 genotypec | 0.57 [0.51–0.63] | 0.45 [0.42–0.47] | 0.69 [0.67–0.71] |
All genotypesc,d (23/24/33/34/44) | 0.58 [0.51–0.64] | 0.67 [0.64–0.70] | 0.66 [0.63–0.68] |