Table 1 Baseline characteristics of the dementia prediction population
From: Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study
Characteristics | No dementia at death (n = 148) | Dementia at death (n = 97) | p Value |
|---|---|---|---|
Follow-up time, years | 5.4 (2.7) | 5.8 (2.6) | 0.3 |
Sociodemographics | |||
Age at baseline, years | 88.4 (2.6) | 88.3 (2.6) | 0.7 |
Men, n (%) | 33 (22%) | 19 (20%) | 0.6 |
Education, years | 4.6 (3.3) | 3.7 (2.0) | 0.01 |
Social class | 6.0 (1.5) | 6.2 (1.3) | 0.2 |
Cognition | |||
MMSE Total | 25.3 (3.3) | 22.2 (4.5) | < 0.001 |
MMSE Calculation | 3.4 (1.6) | 2.9 (1.6) | 0.02 |
MMSE Orientation | 9.5 (0.8) | 8.7 (1.6) | < 0.001 |
MMSE Other tasks | 7.4 (1.2) | 6.7 (1.4) | < 0.001 |
MMSE Wordlist | 5.0 (1.1) | 4.2 (1.3) | < 0.001 |
SPMSQ | 0.8 (1.4) | 1.8 (1.9) | < 0.001 |
Functioning | |||
Competence in daily activities | 2.6 (1.3) | 3.2 (1.4) | 0.001 |
ADL sum (ADL + IADL) | 29.7 (10.2) | 31.6 (10.1) | 0.2 |
Subjective memory decline | 1.7 (0.6) | 1.9 (0.7) | 0.05 |
APOE genotype | |||
ε2ε3 | 17 (12%) | 18 (19%) | 0.02 |
ε2ε4 | 1 (1%) | 5 (6%) | |
ε3ε3 | 101 (69%) | 53 (55%) | |
ε3ε4 | 27 (18%) | 18 (19%) | |
ε4ε4 | 0 (0%) | 1 (1%) | |
Comorbidity, n (%) | |||
Cardiovascular | 114 (77%) | 66 (68%) | 0.1 |
Cerebrovascular | 22(15%) | 19 (20%) | 0.3 |
Diabetes | 29 (20%) | 28 (29%) | 0.09 |
Cholesterol, mmol/L | |||
Total cholesterol | 5.9 (1.3) | 5.7 (1.1) | 0.2 |
LDL cholesterol | 4.0 (1.2) | 3.8 (1.0) | 0.2 |
HDL cholesterol | 1.0 (0.3) | 1.1 (0.3) | 0.2 |
Blood pressure, mmHg | |||
Systolic | 161 (25) | 157 (27) | 0.2 |
Diastolic | 85 (11) | 84 (12) | 0.6 |
Lifestyle factors | |||
BMI | 25.4 (4.4) | 24.9 (3.6) | 0.3 |
No alcohol use, n (%) | 99 (67%) | 67 (69%) | 0.8 |
Nonsmokers, n (%) | 144 (97%) | 95 (98%) | 0.7 |
Depressive symptoms | |||
Zung Self-Rating Depression Scale | 26.8 (5.8) | 26.7 (5.5) | 1 |