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Table 1 Sociodemographic, genetic, mood, and SCDplus features descriptive data in the whole sample

From: Brain and cognitive correlates of subjective cognitive decline-plus features in a population-based cohort

 

Non-SCD group

SCD– group

SCD+ group

N

2098

319

253

Age, mean (SD)

55.41 (6.62)

55.62 (6.22)

59.10 (7.12)*,**

Education, mean (SD)

13.41 (3.52)

13.38 (3.55)

12.83 (3.41)*

Females, n (%)

1316 (62.7%)

218 (68.3%)

154 (60.9%)

GADS—anxiety, mean (SD)

0.49 (1.07)

0.92 (1.51)*

0.90 (1.41)*

GADS—depression, mean (SD)

0.11 (0.52)

0.35 (0.93)*

0.44 (1.07)*

SCDplus features, n (%)

 Worry about the decline

 

165 (51.7%)

223 (88.1%)**

 Change in the last 2 years

 

179 (56.1%)

233 (92.1%)**

 Age > 60 years

 

62 (19.4%)

133 (52.6%)**

 Confirmation by informanta

 

37 (11.6%)

122 (48.2%)**

APOE ε4 carriers

731 (34.8%)

52 (16.3%)*

144 (56.9%)*,**

  1. SCDplus subjective cognitive decline plus, non-SCD not self-reporting cognitive decline, SCD– SCD with ≤ 3 SCDplus features, SCD+ SCD with >3 SCDplus features, SCD subjective cognitive decline, SD standard deviation, GADS Goldberg Anxiety and Depression Scale, APOE apolipoprotein E, ANOVA analysis of variance
  2. aData available in 568 out of 572 participants with SCD
  3. *p < 0.05 as compared to non-SCD; pairwise (Tukey) ANOVA/chi-square test
  4. **p < 0.05 as compared to SCD–; pairwise (Tukey) ANOVA/chi-square test