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Table 1 Characteristics of the study group showing means, standard deviation, and range of the total sample and dichotomized by group

From: Functional connectivity in cognitive control networks mitigates the impact of white matter lesions in the elderly

 

Total sample

HO

MCI

 

N (n women)

230 (115)

140 (71)

90 (44)

 

Age (years)

65.2 ± 7.6

(50–80)

63 ± 6.9

(50–79)

68.6 ± 7.5

(50–80)

**

APOE4 carrier (%)

71 (30%)

(n = 228)

27 (19%)

44 (49%)

**

WML/TIV

0.17 ± 0.37

(0–2.8)

(n = 229)

0.11 ± 0.25

(0–1.5)

0.28 ± 0.48

(0–2.8)

**

Cognitive reserve

 Education

15.8 ± 3.3

(6–29)

16 ± 3.1

(10–25)

15 ± 3.7

(6–29)

 

 MWT

31.9 ± 2.7

(21–37)

32.4 ± 2

(24–37)

31.1 ± 3

(21–37)

 

 Lifestyle index

16.2 ± 2.6

(7–22)

(n = 139)

16.3 ± 2.5

(7–20)

16.1 ± 2.7

(9–22)

 

Cognition

 MMSE

28.7 ± 1.2

(24–30)

29.0 ± 1.1

(26–30)

28.3 ± 1.4

(24–30)

**

 G factor score

0.35 ± 0.8

(−1.6 to 1.8)

−0.55 ± 0.9

(−1.3 to 2.6)

**

 Executive function factor score

0.25 ± 0.6

(−1.2 to 2.7)

−0.39 ± 1.1

(−1.1 to 4.7)

**

 Memory factor score

0.33 ± 0.8

(−1.9 to 1.7)

−0.52 ± 0.9

(−2.5 to 1.3)

**

  1. Numbers are expressed as mean ± standard deviation, the ranges shown in parenthesis
  2. Cognition variables are the factor scores estimated in the latent variable models. Because the latent variables of cognition were scaled by standardization (M = 0; σ = 0), they are not displayed for the whole group. Group-specific average factor score can be thus interpreted as deviations from the whole sample average
  3. White matter lesions (WML) data were missing in one participant (mild cognitive impairment (MCI): n = 1), and lifestyle index was missing in 91 participants (healthy older (HO): n = 61, MCI: n = 12)
  4. APOE4 apolipoprotein E, MMSE Mini-Mental State Examination, MWT German multiple vocabulary test, TIV transcranial intracranial volume
  5. **p < 0.01, independent sample test for continuous variables and chi-square test for categorical variables