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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Neurophysiological signals as predictive translational biomarkers for Alzheimer’s disease treatment: effects of donepezil on neuronal network oscillations in TgF344-AD rats

Fig. 5

Change in occipital-frontal phase locking in response to donepezil treatment. Donepezil on average increases phase locking between occipital cortex and frontal cortex in TgF344-AD rats and decreases phase locking in wild-type (WT) rats. The magnitude of the change in phase-locking values (PLV) from baseline to post-donepezil injection is significant at theta frequencies (*p < 0.05, two-tailed t test)

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Alzheimer's Research & Therapy

ISSN: 1758-9193