| |
Cth_Global
|
Cth_Frontal
|
Cth_Temporal
|
Cth_Parietal
|
Cth_Occipital
|
|---|
|
B
|
p Value
|
B
|
p Value
|
B
|
p Value
|
B
|
p Value
|
B
|
p Value
|
|---|
|
PiB(−) svMCI
|
|
Model 1
|
−0.004
|
0.352
|
−0.005
|
0.278
|
−0.005
|
0.283
|
−0.004
|
0.310
|
−0.001
|
0.800
|
|
Model 2
|
−0.004
|
0.375
|
−0.004
|
0.438
|
−0.004
|
0.398
|
−0.007
|
0.146
|
−0.001
|
0.880
|
|
Model 3
|
−0.001
|
0.823
|
0.001
|
0.859
|
−0.002
|
0.717
|
−0.004
|
0.359
|
0.001
|
0.758
|
|
PiB(−) SVaD
|
|
Model 1
|
−0.016
|
0.028*
|
−0.020
|
0.019*
|
−0.014
|
0.115
|
−0.017
|
0.014*
|
−0.013
|
0.047*
|
|
Model 2
|
−0.020
|
0.024*
|
−0.023
|
0.024*
|
−0.019
|
0.078
|
−0.021
|
0.012*
|
−0.016
|
0.035*
|
|
Model 3
|
−0.020
|
0.029*
|
−0.023
|
0.032*
|
−0.020
|
0.065
|
−0.021
|
0.017*
|
−0.016
|
0.046*
|
- Abbreviations: Cth cortical thickness, PiB Pittsburgh Compound B, svMCI Subcortical vascular mild cognitive impairment, SVaD Subcortical vascular dementia
- * p < 0.05
- Multiple linear regression was performed after controlling for the covariates as follows:
- Model 1: age, sex, ICV, and MMSE control
- Model 2: age, sex, ICV, MMSE, hypertension, diabetes, hyperlipidemia, and smoking control
- Model 3: age, sex, ICV, MMSE, hypertension, diabetes, hyperlipidemia, smoking, sqrtWMH, and sqrtLacune control
