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Table 2 Multivariate analysis for the correlation of education with cerebrovascular disease markers

From: The impact of education on cortical thickness in amyloid-negative subcortical vascular dementia: cognitive reserve hypothesis

 

sqrtWMH volume

sqrtLacunes

B

p Value

B

p Value

PiB(−) svMCI (n = 45)

 Model 1

1.590

0.251

0.053

0.249

 Model 2

0.399

0.769

0.088

0.100

 Model 3

0.035

0.979

0.066

0.172

PiB(−) SVaD (n = 47)

 Model 1

−1.114

0.393

−0.058

0.322

 Model 2

−1.912

0.537

−0.051

0.430

 Model 3

−1.243

0.440

−0.053

0.456

  1. Abbreviations: PiB Pittsburgh Compound B, sqrt Square root, svMCI Subcortical vascular mild cognitive impairment, SVaD Subcortical vascular dementia, WMH White matter hyperintensity
  2. Multiple linear regression was performed after controlling for the covariates as follows:
  3. Model 1: age, sex, ICV, and MMSE control
  4. Model 2: age, sex, ICV, MMSE, hypertension, diabetes, hyperlipidemia, and smoking control
  5. Model 3: age, sex, ICV, MMSE, hypertension, diabetes, hyperlipidemia, smoking, and global cortical thickness control
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Alzheimer's Research & Therapy

ISSN: 1758-9193