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Table 2 Multivariate analysis for the correlation of education with cerebrovascular disease markers

From: The impact of education on cortical thickness in amyloid-negative subcortical vascular dementia: cognitive reserve hypothesis

  sqrtWMH volume sqrtLacunes
B p Value B p Value
PiB(−) svMCI (n = 45)
 Model 1 1.590 0.251 0.053 0.249
 Model 2 0.399 0.769 0.088 0.100
 Model 3 0.035 0.979 0.066 0.172
PiB(−) SVaD (n = 47)
 Model 1 −1.114 0.393 −0.058 0.322
 Model 2 −1.912 0.537 −0.051 0.430
 Model 3 −1.243 0.440 −0.053 0.456
  1. Abbreviations: PiB Pittsburgh Compound B, sqrt Square root, svMCI Subcortical vascular mild cognitive impairment, SVaD Subcortical vascular dementia, WMH White matter hyperintensity
  2. Multiple linear regression was performed after controlling for the covariates as follows:
  3. Model 1: age, sex, ICV, and MMSE control
  4. Model 2: age, sex, ICV, MMSE, hypertension, diabetes, hyperlipidemia, and smoking control
  5. Model 3: age, sex, ICV, MMSE, hypertension, diabetes, hyperlipidemia, smoking, and global cortical thickness control