Table 3 Parameter estimates and significance values for responses by statin inclusive of ApoE status
From: Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer’s dementia?
Statin use | APOE4 Mean | p value | Mean difference | Standard error of the difference | 95% confidence interval of the difference | ||||
|---|---|---|---|---|---|---|---|---|---|
Lower | Upper | ||||||||
0 | |||||||||
Age at death | 1.00 | 79.64 | |||||||
0.00 | 81.86 | 0.014 | −2.228 | 0.895 | −3.999 | −0.457 | Significant | ||
Education level | 1.00 | 15.59 | 0.879 | −0.132 | 0.868 | −1.835 | 1.570 | Not significant | |
0.00 | 15.72 | ||||||||
Estimated onset age | 1.00 | 69.13 | |||||||
0.00 | 72.25 | 0.002 | −3.118 | 0.992 | −5.083 | −1.153 | Significant | ||
Tauopathy | 1.00 | 2.01 | |||||||
0.00 | 0.34 | 0.000 | 1.672 | 0.076 | 1.523 | 1.820 | Significant | ||
Density of neocortical neuritic plaques (amyloid CERAD score) | 1.00 | 2.60 | |||||||
0.00 | 2.32 | 0.000 | 0.271 | 0.075 | 0.123 | 0.419 | Significant | ||
Braak stage | 1.00 | 5.29 | |||||||
0.00 | 4.87 | 0.000 | 0.420 | 0.112 | 0.199 | 0.642 | Significant | ||
1 | |||||||||
Age at death | 1.00 | 76.81 | 0.036 | −4.543 | 2.159 | −8.795 | −0.291 | Significant | |
0.00 | 81.36 | ||||||||
Education level | 1.00 | 14.13 | 0.444 | −1.598 | 2.085 | −5.704 | 2.508 | Not significant | |
0.00 | 15.72 | ||||||||
Estimated onset age | 1.00 | 67.19 | 0.001 | −5.346 | 1.335 | –8.104 | −2.587 | Significant | |
0.00 | 72.53 | ||||||||
Tauopathy | 1.00 | 2.06 | |||||||
0.00 | 0.37 | 0.000 | 1.691 | 0.183 | 1.330 | 2.051 | Significant | ||
Density of neocortical neuritic plaques (amyloid CERAD score) | 1.00 | 2.56 | 0.393 | 0.207 | 0.242 | −0.270 | 0.684 | Not significant | |
0.00 | 2.36 | ||||||||
Braak stage | 1.00 | 5.25 | 0.167 | 0.498 | 0.359 | −0.210 | 1.206 | Not significant | |
0.00 | 4.75 | ||||||||