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Table 3 CRF attenuates the effect of age on WMH

From: Cardiorespiratory fitness attenuates age-associated aggregation of white matter hyperintensities in an at-risk cohort

Variable

β (SE)

t

p

Age

.009 (.003)

3.48

.001

Sex

−.073 (.035)

−2.07

.041

SBP

.000088 (.001)

0.091

.928

FH

.027 (.033)

0.81

.419

BMI

−.001 (.003)

−0.50

.619

APOE4

−.011 (.031)

−0.34

.732

OUES

−.000043 (.000063)

−0.68

.495

Age × OUES

−.000024 (.0000096)

−2.47

.015

  1. CRF cardiorespiratory fitness, WMH white matter hyperintensities, SE standard error, SBP systolic blood pressure, FH family history of Alzheimer’s disease, BMI body mass index, APOE4 apolipoprotein E ε4 allele carriage, OUES oxygen uptake efficiency slope