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Table 3 Association (measured by OR) and performance (measured by AUC) evaluation of diagnostic confidence of Alzheimer disease of each assessment section in predicting the “gold standard” diagnosis

From: The impact of transcranial magnetic stimulation on diagnostic confidence in patients with Alzheimer disease

Assessment

AUC (95% CI)

OR (95% CI)

p Value

Clinical work-up

0.82 (0.74–0.90)

1.05 (1.03–1.07)

4.9 × 10−9

Clinical work-up plus amyloid markers

0.99 (0.98–1)

1.11 (1.08–1.16)

6.1 × 10−8

Clinical work-up plus TMS

0.98 (0.96–1)

1.32 (1.11–1.83)

0.046

  1. TMS Transcranial magnetic stimulation
  2. p Value refers to the statistical significance of ORs
  3. AUC 95% CI: If CI includes 0.5, the AUC is statistically not different from an AUC obtained from a classification by chance
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Alzheimer's Research & Therapy

ISSN: 1758-9193