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Table 3 Unstandardized regression coefficients and model fit indices for all models examining baseline ventricular size on Dementia Rating Scale performance and 2-year change

From: Clinical dementia severity associated with ventricular size is differentially moderated by cognitive reserve in men and women

Models Intercept Linear slope Model fit indices
β SE p Value β SE p Value \( {\upchi}_{\mathrm{M}}^2 \)(dfM) CFI RMSEA (90% CI) SRMR
Independent (n = 510) − 0.202 0.033 0.000 − 0.085 0.026 0.001 13.258 (6), p = 0.039 0.986 0.049 (0.010–0.085) 0.034
E-CR moderation (n = 510) − 0.093 0.032 0.004 − 0.049 0.028 0.079 5.582 (7), p = 0.589 1.000 0.000 (0.000–0.047) 0.013
E-CR moderation by sex
 Male (n = 254) − 0.104 0.041 0.012 − 0.046 0.033 0.167 6.737 (7), p = 0.457 1.000 0.000 (0.000–0.075) 0.035
 Female (n = 256) − 0.076 0.054 0.159 − 0.046 0.052 0.378 5.499 (8), p = 0.703 1.000 0.000 (0.000–0.056) 0.045
L-CR moderation (n = 499) − 0.052 0.021 0.014 0.016 0.015 0.296 7.308 (7), p = 0.398 0.999 0.009 (0.000–0.056) 0.012
L-CR moderation by sex
 Male (n = 252) − 0.033 0.027 0.218 0.015 0.017 0.359 7.265 (7), p = 0.402 0.999 0.012 (0.000–0.079) 0.034
 Female (n = 247) − 0.086 0.034 0.012 0.010 0.033 0.764 7.200 (8), p = 0.515 1.000 0.000 (0.000–0.070) 0.024
CR-P moderation        31.751 (18), p = 0.024 0.973 0.068 (0.025–0.106) 0.058
 (a) Low (n = 133) − 0.382 0.064 0.000 − 0.127 0.055 0.020     
 (b) Intermediate (n = 189) − 0.212 0.052 0.000 − 0.070 0.052 0.177     
 (c) High (n = 177) − 0.069 0.048 0.145 − 0.089 0.032 0.005     
CR-P moderation by sex
 Male        32.143 (18), p = 0.021 0.941 0.097 (0.037–0.150) 0.141
  (a) Low (n = 58) − 0.323 0.080 0.000 − 0.094 0.069 0.171     
  (b) Intermediate (n = 94) − 0.107 0.074 0.151 0.011 0.068 0.875     
  (c) High (n = 100) − 0.107 0.063 0.091 − 0.048 0.032 0.130     
 Female        12.656 (18), p = 0.817 1.000 0.000 (0.000–0.062) 0.078
  (a) Low (n = 75) − 0.455 0.103 0.000 − 0.221 0.098 0.024     
  (b) Intermediate (n = 95) − 0.308 0.067 0.000 − 0.178 0.079 0.025     
  (c) High (n = 77) − 0.026 0.075 0.727 − 0.143 0.065 0.027     
  1. Abbreviations: β Regression estimate, \( {\chi}_M^2 \) Chi-square test of model fit, dfM Degrees of freedom for model fit, CFI Comparative fix index, CR-P Cognitive reserve panel (E-CR + L-CR), E-CR Early-life cognitive reserve, L-CR Later-life cognitive reserve, RMSEA Root mean square error of approximation, SRMR Standardized root mean square residual