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Table 1 Baseline participant characteristics by clinical status

From: Clinical dementia severity associated with ventricular size is differentially moderated by cognitive reserve in men and women

Characteristics

AD

MCI

VCI

FTD

DLB

Total

n

439

77

52

125

30

723

Age, years

71.7 (9.3)

70.3 (8.2)

71.1 (8.2)

66.9 (9.1)

73.2 (8.8)

70.8 (9.4)

Sex, F/M

233/206

47/30

20/32

64/61

10/20

374/349

MMSE

23.0 (4.8)

27.6 (1.9)

25.7 (3.9)

23.1 (6.0)

23.9 (4.4)

23.8 (4.9)

Ventricular sizea, cm3

43.4 (19.9)

31.4 (17.2)

45.6 (24.5)

42.5 (21.2)

42.7 (20.0)

42.1 (20.5)

WMHa, cm3

7.8 (11.1)

3.3 (4.8)

13.2 (17.5)

4.6 (6.8)

7.2 (11.6)

7.1 (10.8)

TIV, cm3

1213.6 (140.2)

1198.0 (121.8)

1225.1 (122.3)

1204.9 (121.1)

1269.5 (127.3)

1213.6 (133.7)

Dementia Rating Scale

117.8 (14.8)

133.5 (7.8)

126.4 (13.7)

115.7 (19.3)

118.7 (14.6)

119.9 (15.9)

NART-R

107.4 (9.9)

110.1 (9.1)

108.3 (10.3)

102.3 (11.0)

110.0 (10.4)

107.1 (10.3)

WAIS vocabulary

42.8 (14.1)

51.3 (9.8)

42.2 (12.5)

34.7 (18.2)

44.8 (13.3)

42.7 (14.5)

Education, years

13.8 (3.8)

14.0 (3.4)

13.7 (3.9)

14.1 (3.9)

13.9 (3.4)

13.9 (3.7)

  1. Abbreviations: AD Alzheimer’s disease, DLB Dementia with Lewy bodies, FTD Frontotemporal dementia, MCI Mild cognitive impairment, MMSE Mini Mental State Examination, NART-R National Adult Reading Test–Revised, TIV Total intracranial volume, VCI Vascular cognitive impairment, WAIS Wechsler Adult Intelligence Scale, WMH White matter hyperintensities
  2. aCorrected for total intracranial volume