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# Table 1 Overall coefficients of variation (CVs), parameters of variance-component models decomposing total variability into between-cluster and within-cluster variability, and corresponding intraclass correlation coefficients (ICCs)

Biomarker | Intracenter scheme | Intercenter scheme | ||||||
---|---|---|---|---|---|---|---|---|

CV (%) | \( \frac{\sqrt{\psi }}{\mu } \) (%) | \( \frac{\sqrt{\theta }}{\mu } \) (%) | ICC | CV (%) | \( \frac{\sqrt{\psi }}{\mu } \) (%) | \( \frac{\sqrt{\theta }}{\mu } \) (%) | ICC | |

Aβ1–42 | 12 | < 0.1 | 12 | < 0.01 | 31 | 28 | 10 | 0.89 |

pTau181 | 3.2 | 3 | 0.8 | 0.93 | 8 | 2.5 | 7 | 0.11 (0.88) |

Albumin | 4 | < 0.1 | 4 | < 0.01 | 10 | 2 | 9 | 0.05 (0.92) |