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Table 1 Descriptive characteristics of the four groups and comparisons (multinomial logistic regression)

From: Sex ratio in dementia with Lewy bodies balanced between Alzheimer’s disease and Parkinson’s disease dementia: a cross-sectional study

  Univariate analysis Multivariate analysis
AD (n = 135,664) DLB (n = 10,309) PDD (n = 3198) PD (n = 8744) AD DLB PDD PD
Mean [SD] Mean [SD] Mean [SD] Mean [SD] Adjusted OR [95% CI] Adjusted OR Adjusted OR [95% CI] Adjusted OR [95% CI]
Age at first consultation with the diagnosis, years 81.42 [7.98] 80.11 [7.84] 79.45 [8.09] 73.86 [10.79] 1.01** [1.01; 1.01] 1 0.99** [0.99; 0.99] 0.97** [0.96; 0.97]
MMSE at ± 1 year after diagnosis 17.71 [5.93] 18.48 [6.24] 19.18 [5.96] 24.26 [5.22] 0.98** [0.98; 0.99] 1 1.03** [1.02; 1.04] 1.26** [1.25; 1.27]
  No. (%) No. (%) No. (%) No. (%) Adjusted OR [95% CI] Adjusted OR Adjusted OR [95% CI] Adjusted OR [95% CI]
Sex
 Female 95,098 (70.1) 5635 (54.7) 1452 (45.4) 3765 (43.1) 1.83** [1.75; 1.92] 1 0.70** [0.64; 0.76] 0.86** [0.81; 0.93]
 Male 40,566 (29.9) 4674 (45.3) 1746 (54.6) 4979 (56.9) 1   1 1   1  
Type of center
 Memory clinic 101,012 (74.5) 6712 (65.1) 2385 (74.6) 4798 (54.9) 1   1 1   1  
 Regional specialized memory clinic 31,320 (23.1) 3226 (31.3) 695 (21.7) 3508 (40.1) 0.76** [0.73; 0.80] 1 0.54** [0.48; 0.60] 0.87** [0.80; 0.94]
 Private practice neurologist 3332 (2.5) 368 (3.6) 118 (3.7) 438 (5.0) 0.66** [0.59; 0.75] 1 0.95 [0.75; 1.20] 1.18* [1.00; 1.40]
Education
 No education 11,075 (8.2) 663 (6.4) 194 (6.1) 334 (3.8) 1.22** [1.09; 1.36] 1 1.20 [0.95; 1.52] 1.88** [1.57; 2.26]
 Primary 64,430 (47.5) 4484 (43.5) 1327 (41.5) 2471 (28.3) 1.06 [0.98; 1.14] 1 1.16 [0.99; 1.35] 1.25** [1.11; 1.39]
 Secondary first cycle 21,516 (15.9) 1759 (17.1) 517 (16.2) 1595 (18.3) 1.04 [0.96; 1.14] 1 1.07 [0.90; 1.28] 1.19** [1.05; 1.34]
 Secondary second cycle 11,971 (8.8) 945 (9.2) 241 (7.5) 1027 (11.8) 1.11* [1.01; 1.23] 1 1.00 [0.82; 1.23] 1.28** [1.11; 1.47]
 Superior 10,510 (7.8) 1110 (10.8) 317 (9.9) 1308 (15.0) 1   1 1   1  
 Unknown 16,162 (11.9) 1348 (13.1) 602 (18.8) 2009 (23.0) 1.00 [0.91; 1.11] 1 1.92** [1.59; 2.30] 2.78** [2.44; 3.18]
Initially referred by
 General practitioner 90,354 (66.6) 5740 (55.7) 1562 (48.8) 3917 (44.8) 1   1 1   1  
 Neurologist 7876 (5.8) 1118 (10.8) 526 (16.5) 2319 (26.5) 0.56** [0.52; 0.61] 1 1.72** [1.49; 1.99] 1.98** [1.79; 2.19]
 Other specialists 14,136 (10.4) 1406 (13.6) 392 (12.3) 679 (7.8) 0.67** [0.63; 0.72] 1 1.05 [0.91; 1.21] 0.75** [0.66; 0.84]
 Direct 5807 (4.3) 389 (3.8) 105 (3.3) 343 (3.9) 0.96 [0.85; 1.08] 1 1.11 [0.87; 1.42] 1.02 [1.85; 1.23]
 Others 17,488 (12.9) 1656 (16.1) 613 (19.2) 1486 (17.0) 0.65** [0.61; 0.70] 1 1.32** [1.16; 1.49] 1.82** [1.65; 2.01]
Community-dwelling
 No 22,756 (16.8) 2045 (19.8) 778 (24.3) 1239 (14.2) 1   1 1   1  
 Yes 112,908 (83.2) 8267 (80.2) 2420 (75.7) 7505 (85.8) 1.37** [1.29; 1.45] 1 0.71** [0.63; 0.79] 0.79** [0.71; 0.87]
Location of the patient
 Within 50 km from the memory clinic 124,519 (91.8) 9220 (89.4) 2899 (90.7) 6816 (78.0) 1.08* [1.00; 1.16] 1 0.97 [0.84; 1.13] 0.61** [0.55; 0.67]
 > 50 km from the memory clinic 11,145 (8.2) 1089 (10.6) 299 (9.4) 1928 (22.0) 1   1 1   1  
  1. Abbreviations: AD Alzheimer’s disease, DLB Dementia with Lewy bodies, PDD Parkinson’s disease dementia, PD Parkinson’s disease, MMSE Mini Mental State Examination
  2. ** p < 0.01; *p < 0.05