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Table 2 Neuropsychological test scores at baseline in patients with and without apathy

From: Apathy is associated with faster global cognitive decline and early nursing home admission in dementia with Lewy bodies

 

Total sample

AD

DLB

Nonapathy

(n = 124)

Apathy

(n = 72)

p Value*

Nonapathy

(n = 85)

Apathy

(n = 35)

p value*

Nonapathy

(n = 39)

Apathy

(n = 37)

p Value*

MMSE total (SD)

23.6 (2.6)

23.4 (2.8)

.415

23.7 (2.5)

23.6 (2.2)

.486

23.4 (3.0)

23.11(3.3)

.736

MMSE pentagon, correct copy (%)

61.8

51.4

.102

70.9

61.8

.340

48.4

45.5

.814

MMSE subtraction/word (SD)

3.7 (1.4)

3.6 (1.6)

.973

4.0 (1.3)

4.0 (1.4)

.593

3.2 (1.5)

3.3 (1.8)

.862

MMSE memory (SD)

1.0 (1.0)

1.0 (1.0)

.886

0.8 (0.9)

0.6 (0.8)

.462

1.4 (0.9)

1.4 (1.1)

.870

CVLT-II List A total (SD)

20.4 (7.5)

18.8 (9.2)

.092

18.5 (6.4)

18.6 (7.7)

.695

24.5 (8.3)

19.1 (10.5)

.020

CVLT-II delayed recall (SD)

1.9 (2.4)

1.6 (2.2)

.416

1.4 (1.9)

1.2 (2.1)

.496

3.1 (2.8)

2.1 (2.3)

.141

VOSP silhouettes (SD)

13.7 (5.0)

12.9 (5.2)

.269

13.8 (5.2)

13.0 (6.2)

.480

13.7 (4.6)

12.8 (4.2)

.084

VOSP cubes (SD)

6.4 (3.1)

6.5 (3.0)

.885

7.2 (2.3)

7.4 (2.3)

.711

5.2 (3.7)

5.6 (3.5)

.652

BNT (SD)

10.1 (2.9)

10.8 (2.9)

.165

10.1 (3.1)

10.4 (3.2)

.644

10.1 (2.4)

11.1 (2.5)

.146

Stroop word (SD)

69.4 (22.9)

62.6 (20.6)

.087

75.9 (22.2)

70.3 (18.3)

.260

55.1 (17.4)

54.4 (20.1)

.111

Stroop color (SD)

44.0 (15.6)

38.5 (14.5)

.021

47.4 (15.6)

43.0 (11.6)

.148

36.3 (12.5)

33.7 (15.9)

.302

Stroop color-word (SD)

16.2 (0.9)

13.4 (8.3)

.133

18.3 (11.5)

13.9 (8.9)

.103

11.5 (7.3)

13.0 (7.7)

.405

COWAT animals (SD)

12.2 (4.4)

10.7 (4.4)

.014

12.3 (4.2)

11.2 (4.4)

.146

12.0 (4.7)

10.3 (4.4)

.108

Trail Making Test A (SD)

111.0 (69.0)

124.2 (92.1)

.686

96.8 (63.7)

113.4 (82.1)

.544

143.1 (70.3)

136.1 (101.9)

.173

Memory domain, z-scores (SD)

0.03 (0.8)

−0.04 (0.9)

.395

−0.17 (0.87)

−0.25 (0.8)

.422

0.48 (0.8)

0.15 (0.9)

.152

Visuospatial domain, z-scores (SD)

0.06 (0.7)

−0.09 (0.7)

.132

0.17 (0.7)

0.06 (0.8)

.406

−0.17 (0.8)

−0.22 (0.69)

.652

Executive domain, z-scores (SD)

0.08 (0.7)

−0.18 (0.8)

.014

0.30 (0.6)

0.05 (0.6)

.104

−0.30 (0.6)

−0.39 (0.8)

.823

  1. Abbreviations: AD Alzheimer’s disease, BNT Boston Naming Test, COWAT Controlled Oral Word Association Test, CVLT-II California Verbal Learning Test, Second Edition, DLB Dementia with Lewy bodies, MMSE Mini Mental State Examination, VOSP Visual Object and Space Perception Battery
  2. *Differences were analyzed using the Mann-Whitney U test and Pearson’s chi-square test
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Alzheimer's Research & Therapy

ISSN: 1758-9193