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Table 2 Neuropsychological test scores at baseline in patients with and without apathy

From: Apathy is associated with faster global cognitive decline and early nursing home admission in dementia with Lewy bodies

  Total sample AD DLB
Nonapathy
(n = 124)
Apathy
(n = 72)
p Value* Nonapathy
(n = 85)
Apathy
(n = 35)
p value* Nonapathy
(n = 39)
Apathy
(n = 37)
p Value*
MMSE total (SD) 23.6 (2.6) 23.4 (2.8) .415 23.7 (2.5) 23.6 (2.2) .486 23.4 (3.0) 23.11(3.3) .736
MMSE pentagon, correct copy (%) 61.8 51.4 .102 70.9 61.8 .340 48.4 45.5 .814
MMSE subtraction/word (SD) 3.7 (1.4) 3.6 (1.6) .973 4.0 (1.3) 4.0 (1.4) .593 3.2 (1.5) 3.3 (1.8) .862
MMSE memory (SD) 1.0 (1.0) 1.0 (1.0) .886 0.8 (0.9) 0.6 (0.8) .462 1.4 (0.9) 1.4 (1.1) .870
CVLT-II List A total (SD) 20.4 (7.5) 18.8 (9.2) .092 18.5 (6.4) 18.6 (7.7) .695 24.5 (8.3) 19.1 (10.5) .020
CVLT-II delayed recall (SD) 1.9 (2.4) 1.6 (2.2) .416 1.4 (1.9) 1.2 (2.1) .496 3.1 (2.8) 2.1 (2.3) .141
VOSP silhouettes (SD) 13.7 (5.0) 12.9 (5.2) .269 13.8 (5.2) 13.0 (6.2) .480 13.7 (4.6) 12.8 (4.2) .084
VOSP cubes (SD) 6.4 (3.1) 6.5 (3.0) .885 7.2 (2.3) 7.4 (2.3) .711 5.2 (3.7) 5.6 (3.5) .652
BNT (SD) 10.1 (2.9) 10.8 (2.9) .165 10.1 (3.1) 10.4 (3.2) .644 10.1 (2.4) 11.1 (2.5) .146
Stroop word (SD) 69.4 (22.9) 62.6 (20.6) .087 75.9 (22.2) 70.3 (18.3) .260 55.1 (17.4) 54.4 (20.1) .111
Stroop color (SD) 44.0 (15.6) 38.5 (14.5) .021 47.4 (15.6) 43.0 (11.6) .148 36.3 (12.5) 33.7 (15.9) .302
Stroop color-word (SD) 16.2 (0.9) 13.4 (8.3) .133 18.3 (11.5) 13.9 (8.9) .103 11.5 (7.3) 13.0 (7.7) .405
COWAT animals (SD) 12.2 (4.4) 10.7 (4.4) .014 12.3 (4.2) 11.2 (4.4) .146 12.0 (4.7) 10.3 (4.4) .108
Trail Making Test A (SD) 111.0 (69.0) 124.2 (92.1) .686 96.8 (63.7) 113.4 (82.1) .544 143.1 (70.3) 136.1 (101.9) .173
Memory domain, z-scores (SD) 0.03 (0.8) −0.04 (0.9) .395 −0.17 (0.87) −0.25 (0.8) .422 0.48 (0.8) 0.15 (0.9) .152
Visuospatial domain, z-scores (SD) 0.06 (0.7) −0.09 (0.7) .132 0.17 (0.7) 0.06 (0.8) .406 −0.17 (0.8) −0.22 (0.69) .652
Executive domain, z-scores (SD) 0.08 (0.7) −0.18 (0.8) .014 0.30 (0.6) 0.05 (0.6) .104 −0.30 (0.6) −0.39 (0.8) .823
  1. Abbreviations: AD Alzheimer’s disease, BNT Boston Naming Test, COWAT Controlled Oral Word Association Test, CVLT-II California Verbal Learning Test, Second Edition, DLB Dementia with Lewy bodies, MMSE Mini Mental State Examination, VOSP Visual Object and Space Perception Battery
  2. *Differences were analyzed using the Mann-Whitney U test and Pearson’s chi-square test