Skip to main content

Table 1 Characteristics of patients with and without apathy at baseline

From: Apathy is associated with faster global cognitive decline and early nursing home admission in dementia with Lewy bodies

  Total sample AD DLB
Nonapathy
(n = 124)
Apathy
(n = 72)
p Value* Nonapathy
(n = 85)
Apathy
(n = 35)
p Value* Nonapathy
(n = 39)
Apathy
(n = 37)
p Value*
AD/DLB (%) 68.5/31.5 48.6/51.4 .006       
Sex, male/female 39/85 33/39 .044 64/21 22/13 .169 21/18 17/20 .491
Age, years (SD) 76.2 (7.2) 75.8 (8.6) .702 75.7 (7.7) 75.7 (7.8) .865 77.3 (5.9) 75.9 (8.2) .382
Education, years (SD) 9.8 (3.1) 9.3 (2.6) .311 9.7 (3.1) 9.2 (2.3) .497 9.9 (3.0) 9.4 (2.9) .400
CDR global (IQR) 0.8 (0.5) 1.0 (0.0) <.001 0.7 (0.5) 1.0 (0.0) <.001 0.9 (0.5) 1.1 (0.4) .072
Depression, NPI (SD) 1.4 (1.9) 3.2 (3.1) <.001 1.4 (1.9) 3.2 (3.1) .001 1.3 (1.8) 3.2 (3.0) .003
UPDRS (SD) 6.4 (10.6) 7.6 (10.4) .175 1.5 (2.6) 2.5 (4.0) .296 15.9 (13.6) 12.4 (12.2) .245
CIRS (SD) 5.5 (2.4) 6.3 (2.7) .034 5.1 (2.1) 5.7 (2.5) .244 6.5 (2.9) 6.8 (2.8) .641
Duration of dementia symptoms before baseline, months (SD) 34.8 (21.9) 40.8 (24.7) .104 32.4 (21.3) 36.6 (22.5) .298 40.0 (22.4) 44.9 (26.4) .396
Dementia medication at baseline, yes (%) 52.7 35.8 .029 51.9 41.2 .296 54.8 30.3 .047
Dementia medication at follow-up 1, yes (%) 74.5 79.6 .477 71.6 80.0 .384 81.5 79.2 .835
  1. Abbreviations: AD Alzheimer’s disease, DLB Dementia with Lewy bodies, CDR Clinical Dementia Rating, CIRS Cumulative Illness Rating Scale, UPDRS Unified Parkinson’s Disease Rating Scale
  2. * Differences were analyzed using the Mann-Whitney U test and Pearson’s chi-square test