Skip to main content
Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: IgM response against amyloid-beta in aging: a potential peripheral protective mechanism

Fig. 4

Amyloid-beta (Aβ)42 peptide-specific antibodies of IgM isotype are increased in aged subjects. The levels of Aβ42-specific antibodies as well as Aβ scrambled peptide were measured from the plasma samples of aged and young subjects using an in-house ELISA. a Dot plots depict the ratio of Aβ-specific IgG and IgM antibodies to scrambled peptide antibodies. Results are shown as mean ± SD of 43 different aged and 43 different young subjects. b Dot plots depict the ratio of Aβ42-specific IgG and IgM antibodies to scrambled peptide antibodies in male and female aged and young subjects. Results are shown as mean ± SD of 9 aged males and 20 young males and 34 aged females and 23 young females. p values are based on two-tailed, unpaired t tests with 95% confidence interval. O.D. optical density

Back to article page