Knight ADRC | ADNI1 | ADNI2 | BIOCARD | HB | Mayo | Sweden | UPenn | UW | |
---|---|---|---|---|---|---|---|---|---|
n = 3146 | 805 | 390 | 397 | 184 | 105 | 433 | 293 | 164 | 375 |
Age (years) | 70.39 ± 9.12 | 77.89 ± 6.89 | 73.28 ± 7.47 | 62.10 ± 9.46 | 67.52 ± 9.24 | 78.73 ± 6.35 | 75.15 ± 7.63 | 71.60 ± 8.98 | 62.35 ± 16 |
Age range (years) | 37–91 | 58–93 | 55–92 | 23–86 | 45–84 | 50–95 | 50–88 | 50–94 | 21–88 |
Male (%) | 46.09 | 60 | 54.91 | 41.53 | 54.29 | 60.51 | 37.54 | 41.46 | 50.67 |
APOE ε4 positive (%) | 40.75 | 50 | 38.29 | 34.43 | 54.29 | 27.5 | 76.11 | 55.56 | 43.28 |
CDR > 0 (%) | 29.34 | 71.28 | 71.03 | 5.43 | – | 22.17 | 100 | 62.8 | 33.33 |
Aβ42 levelsa | 650.40 ± 305.59 | 169.83 ± 56.0 | 179.98 ± 51.31 | 386.90 ± 89.93 | 77.59 ± 23.30 | 331.0 ± 122.21 | 262.43 ± 72.77 | 163.55 ± 53.54 | 141.90 ± 41.42 |
p-tau181 levelsa | 64.94 ± 34.26 | 34.13 ± 18.52 | 38.63 ± 21.21 | 38.94 ± 12.30 | – | 23.16 ± 10.55 | 105.76 ± 41.82 | 36.96 ± 26.80 | 56.56 ± 29.32 |
tau levelsa | 372.40 ± 235.41 | 97.26 ± 52.03 | 79.69 ± 47.79 | 66.56 ± 26.60 | 84.27 ± 36.79 | 104.29 ± 58.06 | 782.20 ± 301.68 | 93.66 ± 54.29 | 61.64 ± 42.77 |